المؤلفون: Juan A Gomez, Trinayan Kashyap, Yun Dai, Alexis Bauer, Yosef Landesman, Steven Grant, Jana L. Dawson, Daniel M. Sullivan, Kenneth H. Shain, Joel G. Turner, Mark B. Meads

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Time Factors, Transcription, Genetic, Receptors, Cytoplasmic and Nuclear, Apoptosis, Mice, SCID, Pharmacology, acquired drug resistance, Bortezomib, chemistry.chemical_compound, 0302 clinical medicine, NF-KappaB Inhibitor alpha, immune system diseases, Mice, Inbred NOD, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Multiple myeloma, Hematology, carfilzomib, Protein Stability, NF-kappa B, 3. Good health, multiple myeloma, Gene Expression Regulation, Neoplastic, Hydrazines, Oncology, 030220 oncology & carcinogenesis, XPO1, Female, RNA Interference, Oligopeptides, medicine.drug, Research Paper, medicine.medical_specialty, Proteasome Endopeptidase Complex, Combination therapy, Active Transport, Cell Nucleus, Karyopherins, Transfection, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Cell Nucleus, Dose-Response Relationship, Drug, business.industry, Cancer, Triazoles, medicine.disease, Carfilzomib, Xenograft Model Antitumor Assays, IκBα, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Proteolysis, Cancer research, Proteasome inhibitor, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98489c6e2519a954c0d72b3e5c986af8Test
http://europepmc.org/articles/PMC5340237Test

المؤلفون: Caryn Weir-Wiggins, Wen Wan, John D. Roberts, Maciej Kmieciak, Viswanathan Ramakrishnan, Loveleen Kang, Rachid Baz, Cody J. Peer, Steven Grant, G. David Roodman, E. Brent Perkins, L. Austin Doyle, Prithviraj Bose, Martha D. Wellons, Robert K. Stuart, A. Dimitrios Colevas, Daniel C. Sullivan, Heidi Sankala, Beata Holkova, Ellen Shrader, William D. Figg, Kevin T. Hogan, Connie Honeycutt, Domenico Coppola, Mary Beth Tombes, Jana L. Dawson

المصدر: Clinical Cancer Research. 20:5652-5662

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Neutropenia, Pharmacology, Article, Drug Administration Schedule, Bortezomib, chemistry.chemical_compound, Piperidines, Recurrence, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Multiple myeloma, Aged, Flavonoids, B-Lymphocytes, Leukopenia, business.industry, Waldenstrom macroglobulinemia, Middle Aged, Alvocidib, medicine.disease, Boronic Acids, Combined Modality Therapy, Lymphoproliferative Disorders, Regimen, Treatment Outcome, chemistry, Pyrazines, Retreatment, Female, Mantle cell lymphoma, Drug Monitoring, medicine.symptom, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390b15badeec929de98b3fd33b94b857Test
https://doi.org/10.1158/1078-0432.ccr-14-0805Test

المؤلفون: Hossein A. Hamed, Paul Dent, Steven Grant, Seyedmehrad Tavallai, Andrew Poklepovic

المصدر: Cancer Biology & Therapy. 15:578-585

مصطلحات موضوعية: Cancer Research, Indazoles, Mice, Nude, Antineoplastic Agents, Biology, Pharmacology, Autophagy-Related Protein 5, Pazopanib, Cell Line, Tumor, Autophagy, medicine, Animals, FADD, Protein kinase B, Vorinostat, PI3K/AKT/mTOR pathway, Sulfonamides, Gene knockdown, Valproic Acid, Membrane Proteins, Drug Synergism, Sarcoma, Receptors, Death Domain, medicine.disease, Histone Deacetylase Inhibitors, Pyrimidines, Oncology, Gene Knockdown Techniques, Cancer research, biology.protein, Molecular Medicine, Beclin-1, Female, Histone deacetylase, Apoptosis Regulatory Proteins, Microtubule-Associated Proteins, Research Paper, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c4c52696d45c8d532ac245ed88ab37Test
https://doi.org/10.4161/cbt.28163Test

المؤلفون: Steven Grant, Paul Dent, Jeremy C. Allegood, Andrew Poklepovic, Sarah Spiegel, Besim Ogretmen, Nichola Cruickshanks, Margaret A. Park, Hossein A. Hamed, M. Danielle Bareford

المصدر: Cancer Biology & Therapy. 13:793-803

مصطلحات موضوعية: Niacinamide, MAPK/ERK pathway, Sorafenib, Cancer Research, medicine.medical_specialty, Ceramide, Guanine, MAP Kinase Signaling System, Pyridines, Antineoplastic Agents, Breast Neoplasms, Endosomes, Pemetrexed, Biology, Receptor, Platelet-Derived Growth Factor beta, chemistry.chemical_compound, Glutamates, Cell Line, Tumor, Internal medicine, Autophagy, medicine, Humans, Protein Phosphatase 2, Extracellular Signal-Regulated MAP Kinases, Ceramide synthase, Pharmacology, Phenylurea Compounds, Benzenesulfonates, Drug Synergism, Protein phosphatase 2, Enzyme Activation, src-Family Kinases, Endocrinology, Oncology, chemistry, Gene Knockdown Techniques, Cancer cell, Cancer research, Molecular Medicine, Female, RNA Interference, Research Paper, Proto-oncogene tyrosine-protein kinase Src, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d42773d08083a74b0e4f8a1a6753dcTest
https://doi.org/10.4161/cbt.20562Test

المؤلفون: Mandy Mayo Aust, Elisa Attkisson, Mohamed Rahmani, Andrea Ferreira-Gonzalez, Steven Grant, David C. Williams

المصدر: Blood. 119:6089-6098

مصطلحات موضوعية: Niacinamide, Sorafenib, Indoles, Pyridines, Immunology, Mice, Nude, Apoptosis, HL-60 Cells, Biology, Biochemistry, Mice, chemistry.chemical_compound, Proto-Oncogene Proteins, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Pyrroles, Clonogenic assay, neoplasms, Cells, Cultured, Gene knockdown, Myeloid Neoplasia, Bcl-2-Like Protein 11, Phenylurea Compounds, Benzenesulfonates, Autophagy, Membrane Proteins, Myeloid leukemia, Drug Synergism, U937 Cells, Cell Biology, Hematology, medicine.disease, Xenograft Model Antitumor Assays, Up-Regulation, Leukemia, Proto-Oncogene Proteins c-bcl-2, chemistry, Leukemia, Myeloid, Cancer research, Female, Apoptosis Regulatory Proteins, Obatoclax, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3eeb95b4fed43aa25d02ce71b086dc3Test
https://doi.org/10.1182/blood-2011-09-378141Test

المؤلفون: John D. Roberts, Viswanathan Ramakrishnan, Loveleen Kang, Steven Grant, Robert K. Stuart, Sarah Kolla, Cody J. Peer, G. David Roodman, Beata Holkova, Kevin T. Hogan, E. Brent Perkins, Ellen Shrader, Domenico Coppola, William D. Figg, Austin Doyle, Martha D. Wellons, John J. Wright, Jana L. Dawson, Neha Talreja, Daniel M. Sullivan, Mary Beth Tombes

المصدر: Clinical Cancer Research. 17:3388-3397

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Lymphoma, B-Cell, Neutropenia, Pharmacology, Drug Administration Schedule, Article, Bortezomib, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Recurrence, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Leukemia, B-Cell, medicine, Humans, Treatment Failure, Multiple myeloma, Aged, 030304 developmental biology, Flavonoids, 0303 health sciences, Leukopenia, business.industry, Middle Aged, Alvocidib, medicine.disease, Boronic Acids, 3. Good health, Regimen, chemistry, Drug Resistance, Neoplasm, Pyrazines, 030220 oncology & carcinogenesis, Female, Mantle cell lymphoma, medicine.symptom, business, Febrile neutropenia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8347ea3ab6b3efd27fa987ecd419a91bTest
https://doi.org/10.1158/1078-0432.ccr-10-2876Test

المؤلفون: Sarah Kolla, Angelika M. Burger, Sunita Philip, Maria R. Baer, Julianne L. Holleran, Olga Goloubeva, Steven Grant, Ashraf Badros, Carolynn Harris, Merrill J. Egorin, John Wright, James A. Zwiebel, Ruben Niesvizky, Igor Espinoza-Delgado

المصدر: Clinical Cancer Research. 15:5250-5257

مصطلحات موضوعية: Adult, Male, Cancer Research, Maximum Tolerated Dose, medicine.drug_class, Pharmacology, Hydroxamic Acids, Drug Administration Schedule, Article, Bortezomib, Recurrence, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Autologous transplantation, Vorinostat, Multiple myeloma, Aged, Lenalidomide, Dose-Response Relationship, Drug, business.industry, Histone deacetylase inhibitor, Middle Aged, medicine.disease, Boronic Acids, Thalidomide, Oncology, Drug Resistance, Neoplasm, Pyrazines, Injections, Intravenous, Proteasome inhibitor, Female, Multiple Myeloma, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbc5aa8d42eb909a23d48034ad19c55Test
https://doi.org/10.1158/1078-0432.ccr-08-2850Test

المؤلفون: Paul B. Fisher, David T. Curiel, Paul Dent, Steven Grant

المصدر: Cancer Biology & Therapy. 8:27-30

مصطلحات موضوعية: Gerontology, Cancer Research, Cell Survival, medicine.disease_cause, Models, Biological, Phosphatidylinositol 3-Kinases, medicine, Humans, HIV Protease Inhibitor, Receptors, Growth Factor, PI3K/AKT/mTOR pathway, Ovarian Neoplasms, Pharmacology, Cisplatin, Mutation, Taxane, business.industry, PTEN Phosphohydrolase, medicine.disease, Enzyme Activation, Oncology, Toxicity, Cancer research, Molecular Medicine, Female, Ovarian cancer, business, Proto-Oncogene Proteins c-akt, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b5eb10d0b13eeb725708527cc47309Test
https://doi.org/10.4161/cbt.8.1.7365Test

المؤلفون: Mandy Mayo Aust, Justin Sperlazza, Catherine I. Dumur, Gordon D. Ginder, Kellie J. Archer, Shreya Podder, Shou Zhen Wang, Sheng Zu Zhu, Steven Grant, Mohamed Rahmani, Jason M. Beckta, Elisa Hawkins

المصدر: Blood. 126(12)

مصطلحات موضوعية: Antimetabolites, Antineoplastic, Myeloid, Daunorubicin, Immunology, Mice, SCID, Biology, Biochemistry, Autoantigens, Chromodomain, Mice, Inbred NOD, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Tumor Cells, Cultured, Animals, Humans, DNA Breaks, Double-Stranded, neoplasms, Antibiotics, Antineoplastic, Myeloid Neoplasia, Cytarabine, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Chromatin, Leukemia, Haematopoiesis, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Cancer research, Female, RNA Interference, medicine.drug, Mi-2 Nucleosome Remodeling and Deacetylase Complex

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc34bd0c5e6a8796cf258c705bac6d6Test
https://pubmed.ncbi.nlm.nih.gov/26265695Test

المؤلفون: Hiral Patel, Johnathan Friedberg, Simon S. Jones, Steven N. Quayle, Girija Dasmahapatra, Steven Grant

المصدر: Molecular cancer therapeutics. 13(12)

مصطلحات موضوعية: Cancer Research, Programmed cell death, Cell cycle checkpoint, DNA damage, Apoptosis, Biology, Histone Deacetylase 6, Hydroxamic Acids, Histone Deacetylases, Article, chemistry.chemical_compound, immune system diseases, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Animals, Humans, Drug Interactions, RNA, Small Interfering, Lymphoma, Non-Hodgkin, Drug Synergism, Cell Cycle Checkpoints, medicine.disease, Carfilzomib, Xenograft Model Antitumor Assays, Lymphoma, Tumor Burden, DNA-Binding Proteins, Histone Deacetylase Inhibitors, Disease Models, Animal, Oxidative Stress, DNA Repair Enzymes, Pyrimidines, Oncology, chemistry, Gene Knockdown Techniques, Immunology, Proteasome inhibitor, Cancer research, Mantle cell lymphoma, Female, Reactive Oxygen Species, Oligopeptides, Proteasome Inhibitors, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8c435023b69a37098187b5728036d0Test
https://pubmed.ncbi.nlm.nih.gov/31160511Test