المؤلفون: Laurence Chiche, Mustapha Adham, Jeanâ€Robert Delpero, Patrick Pessaux, Emmanuel Boleslawski, Daniel Azoulay, Denis Chatelain, Michel Scotté, Karim Boudjema, Alexis Laurent, Jean-Marc Regimbeau, Philippe Bachellier, Gérard Pascal, Jeanâ€Yves Mabrut, Momar Diouf, Olivier Farges, Gennaro Nuzzo, Christian Letoublon, Georges Mantion, Jeanâ€Francois Gigot, Yvesâ€Patrice Le Treut, Artigas Raventos, Francis Navarro, Michel Rivoire, Ahmet Ayav, David Fuks

المساهمون: CHU Amiens-Picardie, CHU Strasbourg, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Service de Chirurgie Viscérale et Digestive [CHU Caen], CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Hôpital Paul Brousse, Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse, Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Département de chirurgie digestive et de l'urgence, CHU Grenoble-Hôpital Michallon, Hôpital Claude Huriez [Lille], CHU Lille, Centre Léon Bérard [Lyon], Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL), Hôpital Edouard Herriot [CHU - HCL], Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service de Chirurgie Digestive Hépatobiliaire et Endocrine [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), CHU Pontchaillou [Rennes], Service de chirurgie digestive [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Hôpital Beaujon, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Herrada, Anthony

المصدر: HPB
HPB, Wiley, 2015, 17 (1), pp.79-86. ⟨10.1111/hpb.12296⟩
HPB, Elsevier, 2015, 17 (1), pp.79-86. ⟨10.1111/hpb.12296⟩

مصطلحات موضوعية: Male, Curative resection, Time Factors, [SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery, medicine.medical_treatment, Kaplan-Meier Estimate, 030230 surgery, Cholangiocarcinoma, 0302 clinical medicine, Risk Factors, Odds Ratio, Registries, Young adult, Aged, 80 and over, Gastroenterology, Middle Aged, Tumor Burden, 3. Good health, Treatment Outcome, 030220 oncology & carcinogenesis, Female, France, Adult, medicine.medical_specialty, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, Resection, Young Adult, 03 medical and health sciences, medicine, Hepatectomy, Humans, Aged, Retrospective Studies, Chi-Square Distribution, Hepatology, business.industry, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Retrospective cohort study, Original Articles, Odds ratio, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Surgery, Bile Ducts, Intrahepatic, Logistic Models, Bile Duct Neoplasms, Tumour size, Multivariate Analysis, Lymph Node Excision, business, Chi-squared distribution

الوصف: International audience; INTRODUCTION:As mortality and morbidity after a curative resection remains high, it is essential to identify pre-operative factors associated with an early death after a major resection.METHODS:Between 1998 and 2008, we selected a population of 331 patients having undergone a major hepatectomy including segment I with a lymphadenectomy and a common bile duct resection for a proven hilar cholangiocarcinoma in 21 tertiary centres. The study's objective was to identify pre-operative predictors of early death (30 mm [odds ratio (OR) 2.471 (95% confidence interval (CI) 1.136-7.339), P = 0.001] and major post-operative complication [OR 3.369 (95% CI 1.038-10.938), P = 0.004] were independently associated with death 30 mm was independently associated with death

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f452c7c76046dba886403c6d8e2f4f0dTest
https://doi.org/10.1111/hpb.12296Test

المؤلفون: A Enriquez, Alexis Laurent, Daniel Azoulay, Chetana Lim, L Lacaze, A. Malek, M Glenisson, C. Salloum, Philippe Compagnon

المصدر: Journal of Visceral Surgery. 151:451-455

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Carcinoma, Hepatocellular, business.industry, Laparoscopic hepatectomy, Liver Neoplasms, Torsion (gastropod), Hepatic lobes, General Medicine, Anatomy, Lobe, Diagnosis, Differential, Radiography, medicine.anatomical_structure, Liver, Accessory liver, medicine, Hepatectomy, Humans, Laparoscopy, Hepatic lobe, business, Accessory lobe, Hepatomegaly

الوصف: Accessory liver lobes are a rare condition and appear to be due to excessive development of the liver. The presence of an accessory hepatic lobe is often diagnosed incidentally and sometimes revealed if it develops torsion, especially in pedunculated forms. In most cases, the accessory lobe is located below the liver, i.e., infrahepatic. Riedel's lobe is the best-known example of an accessory lobe, corresponding to hypertrophy of segments V and VI. While accessories lobes can simulate tumors, there have also been reports of hepatocellular tumor(s) that developed in these accessory lobes. Based on a review of the literature, this update focuses on accessory hepatic lobes.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc97b20fa6db4e00a631c36342bbe9b9Test
https://doi.org/10.1016/j.jviscsurg.2014.09.013Test

المؤلفون: Chady Salloum, Daniel Azoulay, Philippe Compagnon, Julien Calderaro, Alexis Laurent, Daniel Cherqui, Nicola de’Angelis, Emanuele Felli, Riccardo Memeo, Alain Luciani

المصدر: HPB. 16(9):783-788

مصطلحات موضوعية: Laparoscopic surgery, Adult, Male, medicine.medical_specialty, Abdominal pain, Time Factors, medicine.medical_treatment, Asymptomatic, Adenoma, Liver Cell, Risk Factors, medicine, Hepatectomy, Humans, Laparoscopy, Retrospective Studies, medicine.diagnostic_test, Hepatology, business.industry, Liver Neoplasms, Gastroenterology, Retrospective cohort study, Original Articles, Hepatocellular adenoma, Middle Aged, medicine.disease, Surgery, Tumor Burden, Treatment Outcome, Hepatocellular carcinoma, Female, Clinical Competence, France, medicine.symptom, business, Hospital Units

الوصف: Background Hepatocellular adenoma (HCA) is a rare benign liver epithelial tumour that can require surgery. This retrospective study reports a 23-year experience of open and laparoscopic resections for HCA. Methods Patients with a histological diagnosis of HCA were included in this analysis. Surgical resection was performed in all symptomatic patients and in those with lesions measuring > 5 cm. Results Between 1989 and 2012, 62 patients, 59 of whom were female, underwent surgery for HCA (26 by open surgery and 36 by laparoscopic surgery). Overall, 96.6% of female patients had a history of contraceptive use; 54.8% of patients presented with abdominal pain and 11.2% with haemorrhage; the remaining patients were asymptomatic. Patients who underwent laparoscopy had smaller lesions (mean ± standard deviation diameter: 68.3 ± 35.2 mm versus 91.9 ± 42.5 mm; P = 0.022). Operatively, laparoscopic and open liver resection did not differ except in the number of pedicle clamps, which was significantly lower in the laparoscopic group (27.8% versus 57.7% of patients; P = 0.008). Postoperative variables did not differ between the groups. Mortality was nil. Two surgical specimens were classified as HCA/borderline hepatocellular carcinoma. At the 3-year follow-up, all patients were alive with no recurrence of HCA. Conclusions Open and laparoscopic liver resections are both safe and feasible approaches for the surgical management of HCA. However, laparoscopic liver resections may be limited by lesion size and location and require advanced surgical skills.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235d597bfe9ca7ab5328a5cb264c6629Test

المؤلفون: Julien Calderaro, Vincenzo Lizzi, Daniel Azoulay, Pietro Genova, Francesco Esposito, Emilie Bequignon, Nicola de’Angelis, Cécile Charpy, Francesco Brunetti, Filippo Landi

المساهمون: Pietro Genova, Francesco Brunetti, Emilie Bequignon, Filippo Landi, Vincenzo Lizzi, Francesco Esposito, Cecile Charpy, Julien Calderaro, Daniel Azoulay, Nicola de’Angelis

المصدر: World Journal of Surgical Oncology

مصطلحات موضوعية: Male, Herpesvirus 4, Human, Pathology, medicine.medical_specialty, Splenic metastasis, Biopsy, medicine.medical_treatment, Splenectomy, Nasopharyngeal neoplasm, Splenic metastasis, Nasopharyngeal carcinoma, Systematic review, Splenic Neoplasm, Review, 03 medical and health sciences, Rare Diseases, 0302 clinical medicine, Surgical oncology, Nasopharynx, Positron Emission Tomography Computed Tomography, medicine, Carcinoma, Humans, Neoadjuvant therapy, Neoplasm Staging, Nasopharyngeal Carcinoma, medicine.diagnostic_test, business.industry, Splenic Neoplasms, Nasopharyngeal Neoplasms, Chemoradiotherapy, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Neoadjuvant Therapy, Settore MED/18 - Chirurgia Generale, Treatment Outcome, Oncology, Nasopharyngeal carcinoma, Lymphatic Metastasis, 030220 oncology & carcinogenesis, Systematic review, Laparoscopy, 030211 gastroenterology & hepatology, Surgery, business

الوصف: Background: Solitary splenic metastases are a rare occurrence, and the nasopharyngeal carcinoma represents one of the most uncommon primary sources. The present study aimed to describe a rare case of a solitary single splenic metastasis from nasopharyngeal carcinoma and to assess the number of cases of isolated nasopharyngeal carcinoma metastases to the spleen reported in the literature. Main body: We describe the case of a 56-year-old man with a history of nasopharyngeal carcinoma and complete remission after chemo-radiotherapy. Three months after complete remission, positron emission tomography/ computed tomography scan revealed a hypermetabolic splenic lesion without increased metabolic activity in other areas. After laparoscopic splenectomy, the pathology report confirmed a single splenic metastasis from undifferentiated carcinoma of the nasopharyngeal type. The postoperative period was uneventful. We also performed a systematic review of the literature using MEDLINE and Google Scholar databases. All articles reporting cases of splenic metastases from nasopharyngeal carcinoma, with or without histologic confirmation, were evaluated. The literature search yielded 15 relevant articles, which were very heterogeneous in their aims and methods and described only 25 cases of splenic metastases from nasopharyngeal carcinoma. Conclusion: The present review shows that solitary splenic metastases from nasopharyngeal carcinoma are a rare event, but it should be considered in patients presenting with splenic lesions at imaging and a history of primary or recurrent nasopharyngeal carcinoma. No evidence supports a negative impact of splenectomy in patients with solitary splenic metastasis from nasopharyngeal carcinoma.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a864e1edc2c097d9787b835e994db8Test
https://doi.org/10.1186/s12957-016-0941-2Test

المؤلفون: Alain Luciani, Chady Salloum, Michael Osseis, Concepcion Gomez Gavara, Georges Boustany, Philippe Compagnon, Daniel Azoulay, Eylon Lahat, Chetana Lim, Alexandre Doussot

المصدر: Liver Transplantation. 22:1159-1161

مصطلحات موضوعية: Transplantation, medicine.medical_specialty, Hepatology, business.industry, medicine.medical_treatment, Left renal vein, 030230 surgery, Liver transplantation, Inferior vena cava, Surgery, 03 medical and health sciences, 0302 clinical medicine, medicine.vein, Medicine, 030211 gastroenterology & hepatology, business, Ligation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0aac53c97be4449aa34e01152a064a3fTest
https://doi.org/10.1002/lt.24477Test

المؤلفون: Pierre Lozeron, Denis Chemla, Teresa Antonini, Vincent Algalarrondo, Marie Théaudin, Sylvie Dinanian, Anouar Benmalek, Ludivine Eliahou, Dominique Le Guludec, Didier Samuel, François Rouzet, Béatrice Ducot, Michel Slama, David H. Adams, Denis Castaing, Catherine Lacroix, Daniel Azoulay, Cécile Cauquil

المصدر: Journal of the American College of Cardiology. 66(19):2154-2156

مصطلحات موضوعية: Adult, Male, endocrine system, Pathology, medicine.medical_specialty, Time Factors, medicine.medical_treatment, macromolecular substances, 030204 cardiovascular system & hematology, Liver transplantation, 03 medical and health sciences, 0302 clinical medicine, Long term survival, medicine, Humans, Survival rate, Amyloid Neuropathies, Familial, biology, business.industry, Amyloidosis, Point mutation, nutritional and metabolic diseases, Autosomal dominant trait, medicine.disease, Prognosis, United States, nervous system diseases, 3. Good health, Liver Transplantation, Survival Rate, Transthyretin, medicine.anatomical_structure, Peripheral nervous system, biology.protein, Female, business, Cardiology and Cardiovascular Medicine, 030217 neurology & neurosurgery, Follow-Up Studies

الوصف: Familial transthyretin amyloidosis (ATTR) is a rare, life-threatening, autosomal dominant disease involving mainly the heart and the peripheral nervous system due to a point mutation of the transthyretin ( TTR ) gene. By removing the main source of the mutated TTR , liver transplantation (LT) has

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663f32c70de0cda6124c7dd58cdda815Test

المؤلفون: Chetana, Lim, Chady, Salloum, Michael, Osseis, Eylon, Lahat, Concepción, Gómez-Gavara, Philippe, Compagnon, Alain, Luciani, Cyrille, Feray, Daniel, Azoulay

المصدر: HPB : the official journal of the International Hepato Pancreato Biliary Association. 20(3)

مصطلحات موضوعية: Aged, 80 and over, Male, Carcinoma, Hepatocellular, Time Factors, Patient Selection, Clinical Decision-Making, Liver Neoplasms, Middle Aged, Patient Readmission, Decision Support Techniques, Postoperative Complications, Treatment Outcome, Predictive Value of Tests, Risk Factors, Hepatectomy, Humans, Female, France, Prospective Studies, Aged, Neoplasm Staging

الوصف: Western guidelines recommend resection for hepatocellular carcinoma (HCC) in so-called ideal cirrhotic patients with a Barcelona Clinic Liver Cancer (BCLC) stage 0-A tumour. This study compares short-term outcomes following resection between patients defined as ideal and nonideal according to the BCLC guidelines.This prospective single-centre open study (ClinicalTrials.govNCT02145013) included all cirrhotic patients with HCC referred for resection from 2014 to 2016. Mortality, morbidity, unresolved liver decompensation, and readmission were measured.The study population included 65 consecutive patients: 32 (49%) ideal and 33 (51%) nonideal. Ideal and nonideal groups did not differ in mortality (3% vs. 6%; p = 0.57), morbidity (53% vs. 73%; p = 0.10), or unresolved liver decompensation (6% vs. 15%; p = 0.23) at 90 days. The readmission rate was higher in the nonideal (21%) than in the ideal group (3%; p = 0.02).Straying from the current guidelines for resection in a selected subset of nonideal patients doubled the number of resections performed for treating HCC, with satisfactory short-term outcomes. These results argue for the expansion of the acknowledged BCLC guidelines.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::e7a6f9a7ce8b08c3770ca94805fdd090Test
https://pubmed.ncbi.nlm.nih.gov/28935451Test

المؤلفون: Paschalis Gavriilidis, Daniel Azoulay, James Hodson, John Isaac, Robert P. Sutcliffe, Keith J. Roberts, Ravi Marudanayagam

المصدر: HPB : the official journal of the International Hepato Pancreato Biliary Association. 20(1)

مصطلحات موضوعية: medicine.medical_specialty, Funnel plot, medicine.medical_treatment, 030230 surgery, Cochrane Library, 03 medical and health sciences, Liver disease, 0302 clinical medicine, medicine, Hepatectomy, Humans, Survival rate, Colectomy, Hepatology, business.industry, Liver Neoplasms, Gastroenterology, Perioperative, Length of Stay, medicine.disease, Surgery, Survival Rate, Treatment Outcome, 030220 oncology & carcinogenesis, Meta-analysis, business, Colorectal Neoplasms

الوصف: This was a systematic review and meta-analysis to compare outcomes between patients undergoing simultaneous or delayed hepatectomy for synchronous colorectal liver metastases.The optimal strategy for treating liver disease among patients with resectable synchronous colorectal liver metastases (CRLM) is unclear. Simultaneous resection of primary tumour and liver metastases may improve patient experience by reducing the number of interventions. However, there are concerns of increased morbidity compared to delayed resections.A systematic literature search was performed using EMBASE, Medline, Cochrane library and Google scholar databases. Meta-analyses were performed using both random-effects and fixed-effect models. Publication and patient selection bias were assessed with funnel plots and sensitivity analysis.Thirty studies including 5300 patients were identified. There were no statistically significant differences in parameters relating to safety and efficacy between the simultaneous and delayed hepatectomy cohorts. Patients undergoing delayed surgery were more likely to have bilobar disease or undergo major hepatectomy. The average length of hospital stay was six days shorter with simultaneous approach [MD = -6.27 (95% CI: -8.20, -4.34), p 0.001]. Long term survival was similar for the two approaches [HR = 0.97 (95%CI: 0.88, 1.08), p = 0.601].In selected patients, simultaneous resection of liver metastases with colorectal resection is associated with shorter hospital stay compared to delayed resections, without adversely affecting perioperative morbidity or long-term survival.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f1b13ed7cc6bf69d9a57cef5cb5b90Test
https://pubmed.ncbi.nlm.nih.gov/28888775Test

المؤلفون: George Saridis, Theofilos Poutahidis, Kali Makedou, Stavros Iliadis, Dimitrios Giakoustidis, Alexander Hardas, Maria Karamperi, V. Papanikolaou, Paola Andreani, Argyro Zacharioudaki, Alexander Giakoustidis, Satvinder Mudan, A. Sklavos, Katerina Angelopoulou, Vassilios N Papadopoulos, Daniel Azoulay, Kalliopi Tsarea, Thomas Goulopoulos, Apostolos Papalois

المصدر: Oncology letters. 15(1)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Oncogene, Wnt signaling pathway, Articles, Cell cycle, Biology, digestive system diseases, Blockade, 03 medical and health sciences, 030104 developmental biology, Cyclin D1, Oncology, Downregulation and upregulation, Apoptosis, Immunology, Cancer research, Signal transduction

الوصف: Recent evidence has suggested that downregulation of the Wnt/β-catenin signaling pathway may contribute to the development and growth of HCC. Consequently, elements of this pathway have begun to emerge as potential targets for improving outcomes of anti-HCC. Thus, the present study sought to examine the effects of Wnt-1 blockade using the classical diethylnitrosamine (DEN)-induced chemical carcinogenesis mouse model of HCC. The depletion of Wnt-1 using neutralizing antisera was done for ten consecutive days at the age of 9 months and mice were examined for the following 20 days. At that time, DEN-treated mice had multiple variably-sized hepatic cell adenomas. Anti-Wnt-1 was particularly potent in suppressing the expression of critical elements of the Wnt/β-catenin signaling pathway, such as β-catenin and Frizzled-1 receptor, however, not Dickkopf-related protein 1. This effect co-existed with the suppression of Cyclin D1, FOXM1, NF-κΒ and c-Jun commensurate with proliferation and apoptosis blockade in hepatocellular adenomas, and reduced Bcl-2 and c-Met in the serum of mice. Nonetheless, tumor size and multiplicity were found to be unaffected, suggesting that apoptosis may be equally important to proliferation in the context of counteracting DEN induced hepatocellular adenomas of mice.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28cc9af0b18c8215e4988c83754a370Test
https://pubmed.ncbi.nlm.nih.gov/29399175Test

المؤلفون: Sarra El Anbassi, Catherine Cordonnier-Jourdin, Zaid Noorah, Daniel Azoulay, Christine Bonnal, Jean-Claude Merle, Françoise Botterel, Eric Levesque, Nawel Aït-Ammar, Fadi Rizk

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 4; Pages: 862

مصطلحات موضوعية: 0301 basic medicine, Male, Antifungal Agents, beta-Glucans, medicine.medical_treatment, Liver transplantation, invasive fungal infection, Gastroenterology, High morbidity, Spectroscopy, liver transplantation, General Medicine, invasive candidiasis, Middle Aged, Predictive value, Computer Science Applications, Survival Rate, Biomarker (medicine), Female, Proteoglycans, (1,3)-β-d<%2Fspan>-glucan%22">">d-glucan, invasive pulmonary aspergillosis, Adult, medicine.medical_specialty, 030106 microbiology, Biology, Chemoprevention, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, Humans, Physical and Theoretical Chemistry, Mortality, Molecular Biology, Aged, Retrospective Studies, Receiver operating characteristic, (1,3)-β-d-glucan, Organic Chemistry, Invasive pulmonary aspergillosis, medicine.disease, Surgery, ROC Curve, Septic arthritis, 1 3 β d glucan, Biomarkers, Invasive Fungal Infections

الوصف: Invasive fungal infections (IFI) are complications after liver transplantation involving high morbidity and mortality. (1,3)-β-d-glucan (BG) is a biomarker for IFI, but its utility remains uncertain. This study was designed to evaluate the impact of BG following their diagnosis. Between January 2013 and May 2016, 271 liver transplants were performed in our institution. Serum samples were tested for BG (Fungitell®, Associates Cape Code Inc., Falmouth, MA, USA) at least weekly between liver transplantation and the discharge of patients. Nineteen patients (7%) were diagnosed with IFI, including 13 cases of invasive candidiasis (IC), eight cases of invasive pulmonary aspergillosis, and one case of septic arthritis due to Scedosporium apiospernum. Using a single BG sample for the primary analysis of IFI, 95% (21/22) of the subjects had positive BG (>80 pg/mL) at the time of IFI diagnosis. The area under the ROC curves to predict IFI was 0.78 (95% CI: 0.73–0.83). The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of BG for IFI were 75% (95% CI: 65–83), 65% (62–68), 17% (13–21), and 96% (94–97), respectively. Based on their high NPV, the BG test appears to constitute a good biomarker to rule out a diagnosis of IFI.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26822a6539a13a9039c669a3dc564538Test
http://europepmc.org/articles/PMC5412443Test