نتائج البحث - "mitochondrial outer membrane permeabilization"

1

دورية أكاديمية

The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis

المؤلفون: Joshua A. Grosser, Rachel L. Fehrman, Dennis Keefe, Martin Redmon, Robert W. Nickells

المصدر: BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)

مصطلحات موضوعية: BAX, Intrinsic apoptosis, Mitochondrial dysfunction, Mitochondrial outer membrane permeabilization, Mitochondrial fragmentation, Elamipretide (SS31), Medicine, Biology (General), QH301-705.5, Science (General), Q1-390

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-0500Test

الوصول الحر: https://doaj.org/article/a0a3bdfe79184dedbcc355b0d9ece19cTest

View record in DOAJ

النص الكامل

2

دورية أكاديمية

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

المؤلفون: Xiaoke Chi, Dang Nguyen, James M Pemberton, Elizabeth J Osterlund, Qian Liu, Hetal Brahmbhatt, Zhi Zhang, Jialing Lin, Brian Leber, David W Andrews

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: primary murine neurons, MEF cells, BMK cells, apoptosis, Bcl-2 family proteins, mitochondrial outer membrane permeabilization, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/44525Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/3930186c3fd04ad4a33907088e2464c2Test

View record in DOAJ

النص الكامل

3

The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis

المؤلفون: Robert W. Nickells, Martin Redmon, Dennis Keefe, Joshua A. Grosser, Rachel L. Fehrman

المصدر: BMC Research Notes
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Science (General), QH301-705.5, Mitochondrial outer membrane permeabilization, Cell, Apoptosis, Mitochondrion, Elamipretide (SS31), General Biochemistry, Genetics and Molecular Biology, Q1-390, 03 medical and health sciences, 0302 clinical medicine, medicine, Staurosporine, Biology (General), bcl-2-Associated X Protein, biology, Chemistry, Cytochrome c, Intrinsic apoptosis, General Medicine, Elamipretide, Mitochondria, Cell biology, Research Note, 030104 developmental biology, medicine.anatomical_structure, BAX, biology.protein, Medicine, Mitochondrial fragmentation, Mitochondrial dysfunction, Oligopeptides, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4af6c2b33b3bbc0d549b091141f275Test
https://doi.org/10.1186/s13104-021-05613-9Test

4

Apoptotic caspases cut down the immunogenicity of radiation

المؤلفون: Lorenzo Galluzzi, Aitziber Buqué, Maria E. Rodriguez-Ruiz, Jitka Fucikova

المصدر: Oncoimmunology
OncoImmunology, Vol 8, Iss 11 (2019)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71825fe0466cc8b55e13cedcf68eda93Test
https://pubmed.ncbi.nlm.nih.gov/31646103Test

5

Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice

المؤلفون: Li Yang, Aizhen Xiong, Wen-Xing Ding, Hua Wang, Hong-Min Ni, Xiao Yang, Zhengtao Wang, Hiromi Sesaki

المصدر: Redox Biology, Vol 12, Iss, Pp 264-273 (2017)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, Seph, Senephylline, ActD, Actinomycin D, Clinical Biochemistry, Apoptosis, Mitochondrion, Liver injury, MOMP, Mitochondrial outer membrane permeabilization, Biochemistry, EM, Electron microscopy, Mfn1, mitofusin 1, GTP Phosphohydrolases, Senecionine, chemistry.chemical_compound, Gene Knockout Techniques, Mice, 0302 clinical medicine, pJNK, Phosphorylated c-Jun N-terminal kinase, HM, Heavy membrane, CQ, Chloroquine, DHPAs, Dehydropyrrolizidine alkaloids, TMRM, Teramethylrhodamine methyl ester, GSH, Glutathione, LPS, Lipopolysaccharide, lcsh:QH301-705.5, Membrane Potential, Mitochondrial, lcsh:R5-920, Cytochrome c, CYP, Cytochrome P450, Alanine Transaminase, 3. Good health, Mitochondria, OPA1, optic atrophy 1, 030220 oncology & carcinogenesis, Drp1, Dynamin-related protein 1, JNK, c-Jun N-terminal kinase, DNA fragmentation, ZVAD-fmk, Carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone, Mitochondrial fission, Chemical and Drug Induced Liver Injury, H＆E, Hematoxylin and eosin, lcsh:Medicine (General), Microtubule-Associated Proteins, Research Paper, Dynamins, HRP, Horseradish peroxidase, Cell Survival, Drp1, Biology, Mfn2, mitofusin 2, Mitochondrial Proteins, 03 medical and health sciences, TUNEL, Terminal deoxynucleotidyl transferase dUTP nick end labeling, medicine, Animals, Humans, MMP, Mitochondrial membrane potential, Fragmentation (cell biology), PHH, Primary human hepatocyte, Pyrrolizidine Alkaloids, MAPK, Mitogen-activted protein kinases, Organic Chemistry, ALT, Alanine aminotransferase, Mdivi-1, Mitochondrial division inhibitor-1, HSEC, hepatic sinusoidal endothelial cells, medicine.disease, Molecular biology, PAs, Pyrrolizidine alkaloids, Disease Models, Animal, 030104 developmental biology, chemistry, lcsh:Biology (General), GAPDH, Glyceradehyde-3-phosphate dehydrogenase, biology.protein, Hepatocytes, DHR, dehydroretronecine, HSOS, Hepatic sinusoidal syndrome, Sene, Senecionine, PFA, paraformaldehyde, ROS, Reactive oxygen species, VDAC, Voltage-dependent anion channel

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9e6428ec7632340316ab8afa41ea60Test
http://www.sciencedirect.com/science/article/pii/S2213231717300745Test

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Regulation of Apoptosis by the Bcl-2 Family of Proteins: Field on a Brink

المؤلفون: Alexey S. Ladokhin

المصدر: Cells
Cells, Vol 9, Iss 2121, p 2121 (2020)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, 2019-20 coronavirus outbreak, protein–membrane interactions, Antineoplastic Agents, Biology, Pathogenesis, Bcl-2 proteins as therapeutic targets, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, cancer, lcsh:QH301-705.5, mitochondrial outer membrane permeabilization, Sulfonamides, Mitochondrial outer membrane permeabilization, Bcl-2 family, apoptosis, Cancer, General Medicine, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Mitochondria, Cell biology, Gene Expression Regulation, Neoplastic, Editorial, 030104 developmental biology, lcsh:Biology (General), Proto-Oncogene Proteins c-bcl-2, Apoptosis, 030220 oncology & carcinogenesis, Mitochondrial Membranes, Homeostasis, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98367e38fd5d6ea860d79dbb9034c297Test
https://doi.org/10.3390/cells9092121Test

7

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

المؤلفون: Zhi Zhang, Dang Nguyen, Xiaoke Chi, David W. Andrews, Elizabeth J Osterlund, Hetal Brahmbhatt, Brian Leber, James M. Pemberton, Jialing Lin, Qian Liu

المصدر: eLife
eLife, Vol 9 (2020)

مصطلحات موضوعية: 0301 basic medicine, Structural Biology and Molecular Biophysics, Mutant, Sequence (biology), Mitochondrion, 0302 clinical medicine, hemic and lymphatic diseases, Biology (General), Inner mitochondrial membrane, Cells, Cultured, bcl-2-Associated X Protein, mitochondrial outer membrane permeabilization, Cerebral Cortex, Neurons, 0303 health sciences, Bcl-2-Like Protein 11, Chemistry, General Neuroscience, apoptosis, General Medicine, BMK cells, Cell biology, Mitochondria, Membrane, 030220 oncology & carcinogenesis, Mitochondrial Membranes, Molecular mechanism, Medicine, biological phenomena, cell phenomena, and immunity, Research Article, QH301-705.5, Science, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Protein Domains, None, Animals, Humans, MEF cells, 030304 developmental biology, General Immunology and Microbiology, Molecular biophysics, Cell Biology, HCT116 Cells, nervous system diseases, Bcl-2 family proteins, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, Structural biology, Apoptosis, primary murine neurons

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fea2501e20063cec39d32828271031dTest
https://pubmed.ncbi.nlm.nih.gov/31976859Test

8

The third model of Bax/Bak activation: a Bcl-2 family feud finally resolved?

المؤلفون: Xu Luo, Katelyn L. O'Neill, Kai Huang

المصدر: F1000Research

مصطلحات موضوعية: BH3 mimetics, Cell, Apoptosis, Bcl-xL, Review, Mutually exclusive events, General Biochemistry, Genetics and Molecular Biology, Membrane-mediated Spontaneous activation, Bid, Bcl-2 family, medicine, Bad, Activator, Humans, Bim, General Pharmacology, Toxicology and Pharmaceutics, retro-translocation, bcl-2-Associated X Protein, Mitochondrial outer membrane permeabilization, General Immunology and Microbiology, biology, Effector, Chemistry, Activator (genetics), BH3-only proteins, Bak, Direct activation, Mcl-1, Articles, General Medicine, Indirect activation, Cell biology, Sensitizer, de novo activation, Mitochondrial outer membrane, bcl-2 Homologous Antagonist-Killer Protein, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Bax, biology.protein, biological phenomena, cell phenomena, and immunity, auto-activation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0434affb0eb4fe195a5c3717977f4b7cTest
https://doi.org/10.12688/f1000research.25607.1Test

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Measuring and Modeling Apoptosis in Single Cells

المؤلفون: Peter K. Sorger, Sabrina L. Spencer

المصدر: Cell. 144(6):926-939

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ce9be8349bfaa5944b05d447810f39Test

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Lysosomal chymotrypsin B potentiates apoptosis via cleavage of Bid

المؤلفون: Xingyu Zhao, Yang Sun, Fuyu Yang, Jincheng Wang, Kai Zhao, Wenjuan Duan, Qi Miao, Yaping Tu, Taotao Wei, Dongxu Cao

المصدر: Cellular and Molecular Life Sciences. 67:2665-2678

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f2e7edc4e1c055cdd24dafbbd6e2c7Test
https://doi.org/10.1007/s00018-010-0356-0Test

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