التفاصيل البيبلوغرافية
| العنوان: |
The Heart failure and Optimal Outcomes from Pharmacy Study (HOOPS): Rationale, design, and baseline characteristics |
| المؤلفون: |
Lowrie, Richard, Mair, Frances S., Greenlaw, Nicola, Forsyth, Paul, McConnachie, Alex, Richardson, Janice, Khan, Nina, Morrison, Deborah, Messow, Claudia-Martina, Rae, Brian, McMurray, John J. V. |
| بيانات النشر: |
Elsevier B.V. |
| سنة النشر: |
2011 |
| المجموعة: |
Australian Catholic University: ACU Research Bank |
| مصطلحات موضوعية: |
pharmacy, heart failure, randomized controlled trial |
| الوصف: |
Aims: The effect on mortality and morbidity of pharmacist-led intervention to optimize pharmacological therapy in patients with systolic heart failure ( HF ) has not been tested in a large-scale, long-term, clinical trial. Methods: We describe the rationale and design of a UK, primary care-based, prospective cluster-randomized controlled trial of a pharmacist-led intervention in HF and report baseline characteristics of the patients randomized. Eighty-seven practices ( 1092 patients ) were assigned to the intervention arm and 87 practices ( 1077 patients ) to usual care. The average age of patients at baseline was 71 years, 70% were male, 86% were treated with an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker and 62% with a beta-blocker. Data for the primary outcome of death from any cause or hospitalization for HF will be available up to 31 December 2010, giving a mean follow-up of 5 years. More than 750 patients would have experienced the primary outcome during this period. The first secondary outcome is death from any cause or hospitalization for a cardiovascular reason. Deaths and hospitalizations are being identified using the Scottish National Health Service electronic patient record-linkage system ( hence the delay between the end of follow-up and database lock ). Conclusion: This trial is powered to provide a robust evaluation of the effect of pharmacist-led treatment optimization in patients with systolic HF in primary care. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| تدمد: |
1388-9842 |
| العلاقة: |
https://acuresearchbank.acu.edu.au/item/861z1/the-heart-failure-and-optimal-outcomes-from-pharmacy-study-hoops-rationale-design-and-baseline-characteristicsTest; https://doi.org/10.1093/eurjhf/hfr083Test; Lowrie, Richard, Mair, Frances S., Greenlaw, Nicola, Forsyth, Paul, McConnachie, Alex, Richardson, Janice, Khan, Nina, Morrison, Deborah, Messow, Claudia-Martina, Rae, Brian and McMurray, John J. V. (2011). The Heart failure and Optimal Outcomes from Pharmacy Study (HOOPS): Rationale, design, and baseline characteristics. European Journal of Heart Failure. 13(8), pp. 917 - 924. https://doi.org/10.1093/eurjhf/hfr083Test |
| DOI: |
10.1093/eurjhf/hfr083 |
| الإتاحة: |
https://doi.org/10.1093/eurjhf/hfr083Test |
| رقم الانضمام: |
edsbas.9A3CDD39 |
| قاعدة البيانات: |
BASE |
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