المؤلفون: Taylor R. Kavanagh, Barbara Ogorek, William M. Oldham, Nicola Alesi, John M. Asara, Heng-Jia Liu, Adam Handen, Carmen Priolo, Damir Khabibullin, Izabela A. Malinowska, Jane J. Yu, Christian V. Baglini, Darius Ebrahimi-Fakhari, Stephen Y. Chan, Jorge Moscat, Alicia Llorente Lope, Maria T. Diaz-Meco, Afshin Saffari, Julie Nijmeh, Ana Pereira, Mustafa Sahin, Hilaire C. Lam, Andrey A. Parkhitko, Elizabeth P. Henske

المصدر: Cancer Research. 77:3255-3267

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Carcinogenesis, SOD2, Fluorescent Antibody Technique, PINK1, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Tuberous Sclerosis, Sequestosome-1 Protein, Tuberous Sclerosis Complex 2 Protein, Mitophagy, Animals, Buthionine sulfoximine, Inner mitochondrial membrane, Mice, Knockout, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, Glutathione, Immunohistochemistry, Kidney Neoplasms, Mitochondria, Cell biology, Glutamine, Disease Models, Animal, 030104 developmental biology, Oncology, chemistry, Multiprotein Complexes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5c0d7ab40b83d0f58309ae408b502cTest
https://doi.org/10.1158/0008-5472.can-16-2458Test

المؤلفون: Jessie Zhang, Dirk Grimm, Lara Wahlster, Jennifer Werenbeck-Ueding, Fabian Bartz, Darius Ebrahimi-Fakhari, Susanne Theiss, Maria Praggastis, Daniel S. Ory, Brigitte Joggerst-Thomalla, Heiko Runz

المصدر: Human Molecular Genetics

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Cell, Vesicular Transport Proteins, CHO Cells, Biology, Endoplasmic Reticulum, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, Niemann-Pick C1 Protein, hemic and lymphatic diseases, Genetics, medicine, Animals, Humans, Molecular Biology, Genetics (clinical), Glycoproteins, Gene knockdown, Membrane Glycoproteins, Niemann–Pick disease, type C, Cholesterol, Endoplasmic reticulum, Intracellular Signaling Peptides and Proteins, Wild type, Membrane Proteins, nutritional and metabolic diseases, Niemann-Pick Disease, Type C, Articles, General Medicine, Fibroblasts, medicine.disease, nervous system diseases, Cell biology, 030104 developmental biology, medicine.anatomical_structure, chemistry, Gene Knockdown Techniques, Mutation, lipids (amino acids, peptides, and proteins), NPC1, Carrier Proteins, Lysosomes, Cholesterol storage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07cbe738977e277b6fc808ad58cadb2Test
https://doi.org/10.1093/hmg/ddw204Test

المؤلفون: Bradley T. Hyman, Jacqueline Schneider, Eliezer Masliah, Pamela J. McLean, Jochen Klucken, Ursula Schlötzer-Schrehardt, Anne Maria Poehler, Silke Nuber, Juergen Winkler, Edward Rockenstein, Darius Ebrahimi-Fakhari

المصدر: Autophagy. 8:754-766

مصطلحات موضوعية: Male, Genetically modified mouse, Detergents, Mice, Transgenic, Protein aggregation, Biology, Transfection, Models, Biological, Mice, chemistry.chemical_compound, mental disorders, Autophagy, medicine, Animals, Humans, Protein Structure, Quaternary, Molecular Biology, Aged, Aged, 80 and over, Cerebral Cortex, Alpha-synuclein, Synucleinopathies, Lewy body, Dementia with Lewy bodies, Cell Biology, medicine.disease, Immunohistochemistry, Basic Research Paper, nervous system diseases, Solubility, nervous system, chemistry, Biochemistry, alpha-Synuclein, Dementia, Female, Lewy Bodies, Macrolides, Lysosomes, Microtubule-Associated Proteins, Biomarkers, Intracellular, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2b934536b4b7e550d1ac695024e447Test
https://doi.org/10.4161/auto.19371Test

المؤلفون: Vivek K. Unni, Darius Ebrahimi-Fakhari, Pamela J. McLean

المصدر: Autophagy. 8:281-283

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Protein aggregation, Protein degradation, Biology, Models, Biological, Mice, chemistry.chemical_compound, In vivo, Phagosomes, Lysosome, Autophagy, medicine, Animals, Humans, Molecular Biology, Alpha-synuclein, Ubiquitin, Dementia with Lewy bodies, Neurodegeneration, Brain, Parkinson Disease, Cell Biology, medicine.disease, Autophagic Punctum, nervous system diseases, Cell biology, medicine.anatomical_structure, chemistry, Proteasome, Proteolysis, alpha-Synuclein, Lysosomes, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd5352b9e304b6154f62bb60399b142Test
https://doi.org/10.4161/auto.8.2.18938Test

المؤلفون: Darius Ebrahimi-Fakhari, Laiq-Jan Saidi, Lara Wahlster

المصدر: Acta Neuropathologica Communications

مصطلحات موضوعية: Protein Folding, Hsp90, Apoptosis, Review, Protein degradation, Protein aggregation, Hsp70, Pathology and Forensic Medicine, Alpha-synuclein, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 610 Medical sciences Medicine, JUNQ and IPOD, Autophagy, medicine, Animals, Humans, Neurodegeneration, Synucleinopathies, Heat shock protein, Proteasome, biology, Neurodegenerative Diseases, Parkinson Disease, medicine.disease, Co-chaperone, chemistry, Chaperone (protein), Parkinson’s disease, Molecular chaperone, biology.protein, Neurology (clinical), Neuroscience, Molecular Chaperones

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad33f76066e5b23a969fa0f24205a5ffTest
https://doi.org/10.1186/2051-5960-1-79Test

المؤلفون: Ippolita Cantuti-Castelvetri, Edward Rockenstein, Zhanyun Fan, Darius Ebrahimi-Fakhari, Vivek K. Unni, Pamela J. McLean, Bradley T. Hyman, Eliezer Masliah

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(41)

مصطلحات موضوعية: Genetically modified mouse, Proteasome Endopeptidase Complex, Transgene, animal diseases, Green Fluorescent Proteins, Mice, Transgenic, Article, Receptor, Platelet-Derived Growth Factor beta, chemistry.chemical_compound, Mice, Ubiquitin, In vivo, mental disorders, Autophagy, Animals, Humans, RNA, Messenger, Enzyme Inhibitors, Alpha-synuclein, Analysis of Variance, biology, Dose-Response Relationship, Drug, General Neuroscience, Age Factors, Cell biology, nervous system diseases, Drug Combinations, chemistry, Proteasome, nervous system, Gene Expression Regulation, biology.protein, alpha-Synuclein, Signal transduction, Lysosomes, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8670c831ca46c8b1f3c987d5072814Test
https://pubmed.ncbi.nlm.nih.gov/21994367Test