التفاصيل البيبلوغرافية
| العنوان: |
Clinical Remission of Cutaneous Squamous Cell Carcinoma of the Auricle with Cetuximab and Nivolumab. |
| المؤلفون: |
Chen, Alessandra, Ali, Nabilah, Boasberg, Peter, Ho, Allen S. |
| المصدر: |
Journal of Clinical Medicine; Jan2018, Vol. 7 Issue 1, p10, 8p |
| مصطلحات موضوعية: |
SQUAMOUS cell carcinoma, MEDICAL radiography, DIAGNOSTIC imaging, CANCER chemotherapy, CANCER treatment |
| مستخلص: |
Cutaneous squamous cell carcinomas (SCC) affecting the regions of the head and neck can be challenging to resect surgically and refractory to chemotherapy or radiation therapy. Consequently; the treatment of squamous cell carcinomas of the skin is a focus of current research. One such advancement is immunotherapy. Herein we describe clinical remission of invasive, poorly differentiated squamous cell carcinoma of the pre-auricular region with external auditory canal involvement using cetuximab, an epidermal growth factor receptor (EGFR) antibody; and nivolumab, a programmed death receptor-1 (PD-1) antibody. Such durable and comprehensive disease resolution demonstrates the therapeutic potential of cetuximab and nivolumab in surgically challenging, treatment-resistant cutaneous squamous cell carcinoma. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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