التفاصيل البيبلوغرافية
| العنوان: |
First Look at Control-IQ: A New-Generation Automated Insulin Delivery System. |
| المؤلفون: |
Brown, Sue, Raghinaru, Dan, Emory, Emma, Kovatchev, Boris |
| المصدر: |
Diabetes Care; 2018, Vol. 41 Issue 12, p2634-2636, 3p |
| مصطلحات موضوعية: |
TYPE 1 diabetes, HYPOGLYCEMIA, INSULIN therapy, GLYCEMIC control, CLOSED loop systems, BLOOD sugar analysis, BLOOD sugar, BLOOD sugar monitoring, CLINICAL trials, COMPARATIVE studies, HYPOGLYCEMIC agents, INSULIN, INSULIN pumps, RESEARCH methodology, MEDICAL cooperation, PATENTS, RESEARCH, RESEARCH funding, PILOT projects, EVALUATION research |
| مستخلص: |
Objective: To pilot test a new closed-loop control technology to validate it for a further large clinical trial.Research Design and Methods: The t:slim X2 insulin pump with Control-IQ Technology (Tandem Diabetes Care) includes a Dexcom G6 sensor and a closed-loop algorithm implemented in the pump that 1) automates insulin correction boluses, 2) has a dedicated hypoglycemia safety system, and 3) gradually intensifies control overnight, aiming for blood glucose levels of approximately 100-120 mg/dL every morning.Results: Five patients with type 1 diabetes (mean age 52.8 years, 2/3 male/female, mean A1C 6.5%) used Control-IQ in an outpatient setting (hotel) for approximately 37 h. During the closed loop, mean glucose was 129 mg/dL (135/121 mg/dL during the day/night), time within target range 70-180 mg/dL was 87% (82%/94% during the day/night), and time <60 mg/dL was 1.1% (2.0%/0.0% during the day/night).Conclusions: Following this pilot trial, Control-IQ was deployed in several studies, including the large-scale National Institutes of Health International Diabetes Closed-Loop (iDCL) Trial. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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