نتائج البحث - "Lipoxygenase"

1

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition

المؤلفون: Mosaad S. Mohamed, Shahenda Mahgoub, Hend Medhat El-Shanbaky, Rania H. Abd El-Hameed, Sahar A. Ali

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 977-986 (2021)

مصطلحات موضوعية: Chemokine, medicine.drug_class, Inflammation, RM1-950, 01 natural sciences, Anti-inflammatory, Lipoxygenase, Structure-Activity Relationship, 4-Butyrolactone, Heterocyclic Compounds, Drug Discovery, medicine, Humans, 15-LOX inhibitors, Lipoxygenase Inhibitors, Pyridazinone, anti-inflammatory, Pharmacology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Tumor Necrosis Factor-alpha, TNF-α inhibitor, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Cyclooxygenase 2, biology.protein, Tumor necrosis factor alpha, selective COX-2 inhibitor, Cyclooxygenase, Therapeutics. Pharmacology, medicine.symptom, Research Article, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19667daf6d13bb3c9f348e6d97dfab69Test
http://europepmc.org/articles/PMC8118430Test

2

Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides

المؤلفون: Xinchun Chen, Oliver Werz, Lukas K Peltner, Paul M. Jordan, Simona Pace, Kehong Zhang, Alexander Wilhelm Weber, Dagmar Fischer, Robert K. Hofstetter

المصدر: Biomolecules
Volume 11
Issue 5
Biomolecules, Vol 11, Iss 746, p 746 (2021)

مصطلحات موضوعية: 0301 basic medicine, Tripterygium wilfordii glycosides, Tripterygium, Inflammation, Pharmacology, Biochemistry, Microbiology, Article, 03 medical and health sciences, Lipoxygenase, 0302 clinical medicine, Immune system, Tandem Mass Spectrometry, medicine, Humans, Glycosides, ddc:610, Molecular Biology, IC50, Chromatography, High Pressure Liquid, Innate immune system, Arachidonate 5-Lipoxygenase, biology, Chemistry, Macrophages, Thromboxanes, Lipid signaling, biology.organism_classification, lipoxygenase, QR1-502, Immunity, Innate, cyclooxygenase, 030104 developmental biology, Gene Expression Regulation, A549 Cells, Prostaglandin-Endoperoxide Synthases, inflammation, specialized pro-resolving mediators, 030220 oncology & carcinogenesis, Antirheumatic Agents, Lipidomics, biology.protein, Prostaglandins, Tripterygium wilfordii, Cyclooxygenase, medicine.symptom

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea61f265212364eed6b4dfdbb90e984Test

3

Lipoxygenase Inhibition by Plant Extracts

المؤلفون: Drago Šubarić, Maja Molnar, Ivica Strelec, Melita Lončarić, Tihomir Moslavac, Valentina Pavić

المصدر: Biomolecules
Biomolecules, Vol 11, Iss 152, p 152 (2021)

مصطلحات موضوعية: plant extracts, Food spoilage, Lipoxygenase, lcsh:QR1-502, Inflammation, Stimulation, Review, Flowers, 01 natural sciences, Biochemistry, lcsh:Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, medicine, Animals, Arachidonate 15-Lipoxygenase, Humans, Lipoxygenase Inhibitors, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Arachidonate 5-Lipoxygenase, Arachidonic Acid, lipoxygenase, polyphenols, biology, fungi, Fatty Acids, food and beverages, Polyphenols, Hydrogen Peroxide, 3. Good health, 0104 chemical sciences, Oxygen, Plant Leaves, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Polyphenol, biology.protein, Fatty Acids, Unsaturated, Arachidonic acid, medicine.symptom, Oxidation-Reduction, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98b336fb16017d9575d9f866f54f9efTest
http://europepmc.org/articles/PMC7911790Test

4

Impact of polyphenols in phagocyte functions

المؤلفون: Leandro Rodrigues da Cunha, Maria Imaculada Muniz-Junqueira, Tatiana Karla dos Santos Borges

المصدر: Journal of Inflammation Research. 12:205-217

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9355c18950236d009b160a9c0b08cf14Test
https://doi.org/10.2147/jir.s193749Test

5

Mechanism of Action and Interactions between Thyroid Peroxidase and Lipoxygenase Inhibitors Derived from Plant Sources

المؤلفون: Ewa Habza-Kowalska, Dariusz Dziki, Urszula Gawlik-Dziki

المصدر: Biomolecules
Volume 9
Issue 11
Biomolecules, Vol 9, Iss 11, p 663 (2019)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d9abe2623f0e66de739659c8475499Test
http://europepmc.org/articles/PMC6920844Test

6

The lipid biology of sepsis

المؤلفون: David A. Ford, Daniel P. Pike, Kaushalya Amunugama

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100090-(2021)
Journal of Lipid Research

مصطلحات موضوعية: 0301 basic medicine, SIRS, systemic inflammatory response syndrome, TXB2, thromboxane B2, ARDS, LPCAT, lysophosphatidylcholine acyltransferase, HOCl, hypochlorous acid, MPO, myeloperoxidase, AA, arachidonic acid, 030204 cardiovascular system & hematology, Bioinformatics, Biochemistry, Pathogenesis, TPPU, N-[1-(1-oxopropyl)-4-piperidinyl]-N′-[4-(trifluoromethoxy)phenyl]-urea, chemistry.chemical_compound, PC, phosphatidylcholine, 0302 clinical medicine, Endocrinology, AEA, N-arachidonoylethanolamine, prognostics, lipid metabolism, DHET, dihydroxyeicosatrienoic acid, LOX, lipoxygenase, 2-ClSA, 2-chlorostearic acid, ATX, autotaxin, cys-LTs, cysteinyl leukotrienes, Rv, resolvin, TG, triglycerides, CLP, cecal ligation puncture, Lipids, SPMs, specialized pro-resolving mediators, 2-ClFALD, 2-chlorofatty aldehyde, LPS, lipopolysaccharide, RvE1-RvE3, E series resolvins, sPLA2, secretory phospholipase A2, medicine.symptom, Resolvin, LPA, lysophosphatidic acid, bioactive lipids, CEPT, cholesteryl ester transfer, rHDL, recombinant HDL, LTB4, leukotriene B4, RvT1-RvT4, T series resolvins, Inflammation, Cer, ceramide, CS, cecal slurry, QD415-436, Biology, fatty acids, TLR, Toll-like receptors, Sepsis, 03 medical and health sciences, 2-ClFA, 2-chlorofatty acid, medicine, energy imbalance, Humans, cPLA2, cytosolic PLA2, PAF, platelet-activating factor, ARDS, acute respiratory distress syndrome, RvD1-RvD6, D series resolvins, DPA, docosapentaenoic acid, S1P, sphingosine-1-phosphate, 2-ClPA, 2- chloropalmitic acid, LPC, lysophosphatidylcholine, Organ dysfunction, PLA2, phospholipase A2, EET, epoxy-eicosatrienoic acid, cholesterol, biomarkers, resolution, Lipid metabolism, Thematic Review Series, Cell Biology, Sphk, sphingosine kinase, SOFA, sequential organ failure assessment, medicine.disease, sEH, soluble epoxide hydrolase, Systemic inflammatory response syndrome, COX, cyclooxygenase, TC, total cholesterol, 030104 developmental biology, chemistry, LTA, lipotechoic acid, inflammation, 10S,17S- diHDHA, 10(S),17(S) dihydroxy docosahexaenoic acid, sepsis pathogenesis, CYP450, cytochrome P450, PCSK9, proprotein convertase subtilisin/kexin type 9, 2-AG, 2-Arachidonoylglycerol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23db04bb22e75ea402d09634f0b80e92Test
http://www.sciencedirect.com/science/article/pii/S0022227521000729Test

7

Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction

المؤلفون: Laurence M. Black, Kevin A. Ingle, Ganesh V. Halade, Vasundhara Kain, Sumanth D. Prabhu

المصدر: Aging (Albany NY)

مصطلحات موضوعية: Male, 0301 basic medicine, Aging, medicine.medical_specialty, Chemokine, Docosahexaenoic Acids, Interleukin-1beta, Population, Myocardial Infarction, Infarction, Inflammation, lipid mediators, 030204 cardiovascular system & hematology, Protectin D1, Mice, 03 medical and health sciences, Lipoxygenase, chemistry.chemical_compound, 0302 clinical medicine, Lipocalin-2, Internal medicine, Animals, Medicine, education, chemistry.chemical_classification, education.field_of_study, biology, Tumor Necrosis Factor-alpha, business.industry, Fatty acid, Cell Biology, medicine.disease, lipoxygenase, macrophages, non-resolving inflammation, 030104 developmental biology, Endocrinology, Eicosapentaenoic Acid, chemistry, Biochemistry, biology.protein, Arachidonic acid, medicine.symptom, business, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d9291b89195c49a2a00d9bcda689e9Test
https://doi.org/10.18632/aging.101077Test

8

Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators

المؤلفون: Romain A. Colas, Agua Sobrino, Mary Walker, Jesmond Dalli

المصدر: PLOS ONE
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0242543 (2020)

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Male, Mice, Knockout, ApoE, Gene Expression, 030204 cardiovascular system & hematology, Pharmacology, Biochemistry, Vascular Medicine, Mice, White Blood Cells, 0302 clinical medicine, Medical Conditions, Animal Cells, Gene expression, Medicine and Health Sciences, Arachidonate 15-Lipoxygenase, Lipoxygenase Inhibitors, Immune Response, Principal Component Analysis, Multidisciplinary, Chemistry, Eukaryota, Plants, Lipids, Lipoproteins, LDL, Lipoxins, Cell Processes, Medicine, Female, medicine.symptom, Cellular Types, Research Article, Leukotrienes, Algae, Phagocytosis, Science, Immune Cells, Inflammatory Diseases, Primary Cell Culture, Immunology, Inflammation, 03 medical and health sciences, Lipid Mediators, Apolipoproteins E, Signs and Symptoms, Downregulation and upregulation, Fatty Acids, Omega-3, medicine, Animals, Humans, Arachidonate 5-Lipoxygenase, Blood Cells, Macrophages, fungi, Organisms, Biology and Life Sciences, Lipid signaling, Cell Biology, Atherosclerosis, In vitro, 030104 developmental biology, Cell culture, Diet, Western, Dietary Supplements, Prostaglandins, Clinical Medicine, Oils

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5165e1943bf439897bf8b97869c08aceTest

9

Pinosylvin exacerbates LPS-induced apoptosis via ALOX 15 upregulation in leukocytes

المؤلفون: Heonyong Park, Ohseong Kwon, Youngsik Seo

المصدر: BMB Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a69bfd247e74fa04199bf71468520cTest
https://doi.org/10.5483/bmbrep.2018.51.6.024Test

10

Inhibitors of Eicosanoid Biosynthesis Reveal that Multiple Lipid Signaling Pathways Influence Malaria Parasite Survival in Anopheles gambiae

المؤلفون: Hyeogsun Kwon, Ryan C. Smith

المصدر: Insects
Volume 10
Issue 10
Insects, Vol 10, Iss 10, p 307 (2019)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd3e0a1f04aa2dca17f641466f4c851Test

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