المؤلفون: Yiyang Chen, Jesse D. Gelles, Jarvier N. Mohammed, Jerry Edward Chipuk

المصدر: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

مصطلحات موضوعية: apoptosis, BAX, BCL-2 family, mitochondria, mitochondrial outer membrane permeabilization, recombinant protein production, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fcell.2023.1322816/fullTest; https://doaj.org/toc/2296-634XTest

الوصول الحر: https://doaj.org/article/ad1c5e974e5b4f44951c3ad2fc7fdb0eTest

المؤلفون: Hantusch, Annika, Rehm, Markus, Brunner, Thomas

المصدر: The FEBS Journal. 2018, 285(22), pp. 4124-4138. ISSN 0014-2956. eISSN 1742-4658. Available under: doi:10.1111/febs.14516

مصطلحات موضوعية: apoptosis, Bcl-2 family, dynamic equilibria, kinetics, mitochondrial outer membrane permeabilization, systems biology, ddc:570

وصف الملف: application/pdf

العلاقة: http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1avtn44ywrh1m6Test; http://dx.doi.org/10.1111/febs.14516Test

الإتاحة: https://doi.org/10.1111/febs.14516Test
http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1avtn44ywrh1m6Test

المؤلفون: Alexey S. Ladokhin

المصدر: Cells
Cells, Vol 9, Iss 2121, p 2121 (2020)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, 2019-20 coronavirus outbreak, protein–membrane interactions, Antineoplastic Agents, Biology, Pathogenesis, Bcl-2 proteins as therapeutic targets, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, cancer, lcsh:QH301-705.5, mitochondrial outer membrane permeabilization, Sulfonamides, Mitochondrial outer membrane permeabilization, Bcl-2 family, apoptosis, Cancer, General Medicine, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Mitochondria, Cell biology, Gene Expression Regulation, Neoplastic, Editorial, 030104 developmental biology, lcsh:Biology (General), Proto-Oncogene Proteins c-bcl-2, Apoptosis, 030220 oncology & carcinogenesis, Mitochondrial Membranes, Homeostasis, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98367e38fd5d6ea860d79dbb9034c297Test
https://doi.org/10.3390/cells9092121Test

المؤلفون: Jing Deng

المصدر: Acta Pharmaceutica Sinica B, Vol 7, Iss 1, Pp 18-26 (2017)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, BTK, Bruton׳s tyrosine kinase, T-ALL, T-acute lymphocytic leukemia, Apoptosis, Review, PI3K, phosphatidylinositol-3-kinase, Targeted therapy, NIH, National Institutes of Health, ERK, extracellular signal-regulated kinase, GSK-3, MOMP, mitochondrial outer membrane permeabilization, BCL-2 family, CML, chronic myelogenous leukemia, General Pharmacology, Toxicology and Pharmaceutics, CDK, cyclin-dependent kinase, CLL, chronic lymphocytic leukemia, BAX, BCL-2-associated X protein, GSK-3, glycogen synthase kinase-3, Cell biology, NHL, non-Hodgkin lymphoma, BOK, BCL-2 related ovarian killer, BCL-xL, B-cell lymphoma X long, Programmed cell death, CHOP, cyclophosphamide, hydroxydaunorubicin, oncovin-vincristine and prednisone, FDA, U. S. Food and Drug Administration, PUMA, p53 up-regulated modulator of apoptosis, ASH, American Society of Hematology, BID, BH3 interacting domain death agonist, BH3 profiling, Bcl-xL, BIM, BCL-2-interacting mediator of cell death, Biology, BCL-w (BCL2L2), BCL-2-like protein 2, BCR, B-cell receptor, ER, endoplasmic reticulum, 03 medical and health sciences, Mitochondrial priming, Cyclin-dependent kinase, SLL, small lymphocytic lymphoma, NSCLC, non-small cell lung cancer, Combination therapy, PI3K/AKT/mTOR pathway, ITK, interleukin-2-inducible T-cell kinase, BH3, BCL-2 homology 3, Bcl-2 family, lcsh:RM1-950, ATAP, amphipathic tail-anchoring peptide, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, biology.protein, BAD, BCL-2-associated death promoter protein, MCL, myeloid cell leukemia, BAK, BCL-2 homologous antagonist killer, BCL-2, B-cell lymphoma 2, BFL-1 (BCL2A1), BCL-2-related protein A1, BIK, BCL-2-interacting killer, CR, complete response, EGFR, epidermal growth factor receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd33a3c642c227ee36c739b38c6e8328Test

المؤلفون: Xu Luo, Katelyn L. O'Neill, Kai Huang

المصدر: F1000Research

مصطلحات موضوعية: BH3 mimetics, Cell, Apoptosis, Bcl-xL, Review, Mutually exclusive events, General Biochemistry, Genetics and Molecular Biology, Membrane-mediated Spontaneous activation, Bid, Bcl-2 family, medicine, Bad, Activator, Humans, Bim, General Pharmacology, Toxicology and Pharmaceutics, retro-translocation, bcl-2-Associated X Protein, Mitochondrial outer membrane permeabilization, General Immunology and Microbiology, biology, Effector, Chemistry, Activator (genetics), BH3-only proteins, Bak, Direct activation, Mcl-1, Articles, General Medicine, Indirect activation, Cell biology, Sensitizer, de novo activation, Mitochondrial outer membrane, bcl-2 Homologous Antagonist-Killer Protein, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Bax, biology.protein, biological phenomena, cell phenomena, and immunity, auto-activation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0434affb0eb4fe195a5c3717977f4b7cTest
https://doi.org/10.12688/f1000research.25607.1Test

المؤلفون: Scott H. Kaufmann, Haiming Dai, X. Wei Meng

المصدر: Cancer Translational Medicine, Vol 2, Iss 1, Pp 7-20 (2016)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, BH3 domain, Bcl-2 family, BAK/BAX activation, Apoptosis, General Medicine, Biology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Mitochondrial apoptosis-induced channel, lcsh:RC254-282, Homology (biology), Cell biology, 03 medical and health sciences, 030104 developmental biology, Immune system, B-cell lymphoma-2 family, hemic and lymphatic diseases, Signal transduction, biological phenomena, cell phenomena, and immunity, Tissue homeostasis, mitochondrial outer membrane permeabilization

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e21b7057b996ae0814d4df51e61b69fTest
http://www.cancertm.com/article.asp?issn=2395-3977;year=2016;volume=2;issue=1;spage=7;epage=20;aulast=DaiTest

المؤلفون: Sanjeev Gupta, Karolina Pakos-Zebrucka, Peter Vandenabeele, Susan E. Logue, Mathieu J.M. Bertrand, Afshin Samali, Svetlana Saveljeva, Shane Deegan

المصدر: Autophagy

مصطلحات موضوعية: endoplasmic-reticulum stress, Fas-Associated Death Domain Protein, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, ATG, autophagy related, chain, DDIT3, DNA-damage-inducible transcript 3, Endoplasmic Reticulum, Autophagy-Related Protein 7, caspase-8, Autophagy-Related Protein 5, cytochrome-c, FADD, Fas (TNFRSF6)-associated via death domain, Mice, 0302 clinical medicine, HSPA5, heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa), MOMP, mitochondrial outer membrane permeabilization, FADD, Endoplasmic Reticulum Chaperone BiP, Caspase, TNF, tumor necrosis factor, Caspase 8, 0303 health sciences, biology, Caspase 3, MEFs, mouse embryonic fibroblasts, BCL2, B-cell CLL/lymphoma 2, apoptosis, BAK1, BCL2-antagonist/killer 1, unfolded protein response, Caspase 9, Mitochondria, Cell biology, BAX, BCL2-associated X protein, autophagic cell death, 030220 oncology & carcinogenesis, endoplasmic reticulum stress, Tm, tunicamycin, roles, Microtubule-Associated Proteins, PARP, poly (ADP-ribose) polymerase, Signal Transduction, DISC, death inducing signaling complex, autophagy, Programmed cell death, Basic Research Papers, assays, caspase, fadd, ATG5, PBS, phosphate-buffered saline, ER, endoplasmic reticulum, PI, propidium iodide, 03 medical and health sciences, Animals, Humans, Molecular Biology, 030304 developmental biology, Bcl-2 family, Cell Biology, Fibroblasts, cell-death, Enzyme Activation, MAP1LC3 (LC3), microtubule-associated protein 1 light chain 3, HEK293 Cells, Gene Expression Regulation, DTT, dithiothreitol, TNFSF10, tumor necrosis factor (ligand) superfamily, member 10, Tg, thapsigargin, biology.protein, activation, bcl-2 family

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f28c796284ac70d3b03988c7d028edTest
https://doi.org/10.4161/15548627.2014.981790Test

المؤلفون: Ana J. García-Sáez, Aida Peña-Blanco

المصدر: The FEBS journal. 285(3)

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Lipid Bilayers, Apoptosis, Biology, Mitochondrion, Biochemistry, Mitochondrial Dynamics, Mitochondrial Membrane Transport Proteins, Models, Biological, 03 medical and health sciences, Organelle, Animals, Humans, Protein Interaction Domains and Motifs, Molecular Biology, bcl-2-Associated X Protein, Mitochondrial outer membrane permeabilization, Bcl-2 family, Lipid Mobilization, Cell Biology, Cell biology, Mitochondria, 030104 developmental biology, bcl-2 Homologous Antagonist-Killer Protein, Proto-Oncogene Proteins c-bcl-2, Mitochondrial Membranes, Molecular mechanism, biological phenomena, cell phenomena, and immunity, Protein Multimerization, Bacterial outer membrane, Apoptosis Regulatory Proteins, Dimerization, Porosity, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c8198ea856de35493a758dc01f311aTest
https://pubmed.ncbi.nlm.nih.gov/28755482Test

المؤلفون: Sanjeev Gupta, George E.N. Kass, Eva Szegezdi, Bertrand Joseph

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Mitochondrial Diseases, bcl-2, amyotrophic-lateral-sclerosis, Reviews, Cellular homeostasis, Mitochondrion, Biology, Models, Biological, Mitochondrial apoptosis-induced channel, cytochrome-c release, peripheral benzodiazepine-receptor, apoptosis-inducing factor, etoposide-induced apoptosis, Animals, Humans, bcl-2 family-members, adenine-nucleotide translocator, bcl-2-Associated X Protein, mitochondrial outer membrane permeabilization, programmed cell-death, Membrane Potential, Mitochondrial, permeability transition pore, Bcl-2 family, apoptosis, Cell Biology, Mitochondria, Cell biology, Proto-Oncogene Proteins c-bcl-2, caspases, electron-transport chain, mitochondrial fusion, Mitochondrial permeability transition pore, DNAJA3, Molecular Medicine, Apoptosome, Signal Transduction, mitochondrial permeability transition

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec68702ae94c60ab920038189210eb7Test
https://doi.org/10.1111/j.1582-4934.2009.00697.xTest

المؤلفون: Clara Pereira, Manuela Côrte-Real, Björn Johansson, Maria João Sousa, Lucília Saraiva, Rui D. Silva

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1783(7):1286-1302

مصطلحات موضوعية: Programmed cell death, Mitochondrial outer membrane permeabilization, Cell, Apoptosis, Yeast apoptosis, Mitochondrion, Biology, Mitochondrial Proteins, 03 medical and health sciences, Bcl-2 family, Yeasts, medicine, Molecular Biology, 030304 developmental biology, 0303 health sciences, 030302 biochemistry & molecular biology, Apoptotic regulators, Cell Biology, Permeability transition pore, Yeast, Cell biology, Mitochondria, medicine.anatomical_structure, Cell metabolism, Biochemistry, Mitochondrial Membranes, Mitochondrial fragmentation, Signal transduction, Apoptosis Regulatory Proteins, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3e150ebf538cb37cad29a33c41ae8aTest