المؤلفون: Ekkehard Schuetz, Simon Villa-Perez, Ingo Nolte, Leila Taher, Barbara C. Ruetgen, Julia Beck, Christian Junghanss, Anett Sekora, Bertram Brenig, Yixuan Ma, Sina Sender, Hugo Murua Escobar, Weibo Kong

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 12673, p 12673 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12673
International Journal of Molecular Sciences

مصطلحات موضوعية: BCR signaling pathway, BTK inhibitor, PI3K inhibitor, DLBCL, gene variants, QH301-705.5, Apoptosis, Article, Catalysis, Inorganic Chemistry, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, Dogs, Piperidines, hemic and lymphatic diseases, Agammaglobulinaemia Tyrosine Kinase, Tumor Cells, Cultured, medicine, Animals, Bruton's tyrosine kinase, Physical and Theoretical Chemistry, Biology (General), Molecular Biology, Protein kinase B, QD1-999, Spectroscopy, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, biology, Cell growth, Adenine, Organic Chemistry, Drug Synergism, General Medicine, BCR Signaling Pathway, medicine.disease, Computer Science Applications, Chemistry, chemistry, Ibrutinib, Cancer research, biology.protein, Drug Therapy, Combination, Lymphoma, Large B-Cell, Diffuse, Diffuse large B-cell lymphoma, Tyrosine kinase, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c102ea5d258a9c4bbcb9a7f936d11f42Test
https://www.mdpi.com/1422-0067/22/23/12673Test

المؤلفون: Christian Junghanss, Anett Sekora, Weibo Kong, Hugo Murua Escobar, Simon Villa Perez, Ingo Nolte, Sina Sender, Barbara C. Ruetgen

المصدر: Anticancer Research. 40:3781-3792

مصطلحات موضوعية: Cancer Research, Indazoles, Syk, Protein Serine-Threonine Kinases, Cell morphology, Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 4 or More Rings, Piperazines, BET inhibitor, 03 medical and health sciences, Dogs, 0302 clinical medicine, In vivo, Cell Line, Tumor, hemic and lymphatic diseases, medicine, Animals, Protein Isoforms, Syk Kinase, Canine Lymphoma, Chemistry, Nuclear Proteins, hemic and immune systems, General Medicine, medicine.disease, Lymphoma, Pyridazines, Oncology, Cell culture, Apoptosis, Pyrazines, 030220 oncology & carcinogenesis, Cancer research, Pyrazoles, Lymphoma, Large B-Cell, Diffuse

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0dd9c7937cd8891b2f175e4f7469a51Test
https://doi.org/10.21873/anticanres.14367Test

المؤلفون: Gudrun Knuebel, Rico Schwarz, Burkhard Hinz, Catrin Roolf, Christian Junghanss, Annemarie Lenz, Sina Sender, Anna Richter, Hugo Murua Escobar, Anett Sekora

المصدر: BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cell Survival, CK2, BCL6, Down-Regulation, Apoptosis, BACH2, lcsh:RC254-282, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Genetics, medicine, Animals, Humans, Naphthyridines, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Oncogene, Chemistry, CX-4945, AKT, B-ALL, CDC42, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Molecular biology, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Basic-Leucine Zipper Transcription Factors, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Luminescent Measurements, Proto-Oncogene Proteins c-bcl-6, Phenazines, Bone marrow, Casein kinase 2, Signal transduction, Pharmakokinetic, Research Article, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0037f3fcdae67a1bb195f8147c3bab16Test
http://europepmc.org/articles/PMC7057698Test

المؤلفون: Anett Sekora, Hugo Murua Escobar, Julia Schulze, Sandra Lange, Catrin Roolf, Anna Richter, Elisabeth Fischer, Gudrun Knuebel, Larissa Henze, Clemens Holz, Christian Junghanss

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 2771, p 2771 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 5

مصطلحات موضوعية: Male, 0301 basic medicine, Mice, SCID, lcsh:Chemistry, Mice, chemistry.chemical_compound, 0302 clinical medicine, Mice, Inbred NOD, Antineoplastic Combined Chemotherapy Protocols, lcsh:QH301-705.5, Spectroscopy, Sulfonamides, apoptosis, General Medicine, Computer Science Applications, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, MK-2206, 030220 oncology & carcinogenesis, Female, Heterocyclic Compounds, 3-Ring, acute lymphoblastic leukemia, Article, AKT inhibition, Catalysis, Inorganic Chemistry, 03 medical and health sciences, MK‑2206, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, B cell, venetoclax, Cell growth, Venetoclax, Organic Chemistry, Bridged Bicyclo Compounds, Heterocyclic, Xenograft Model Antitumor Assays, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, chemistry, Cell culture, Apoptosis, Cancer research, Proto-Oncogene Proteins c-akt

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a639f2678be3444f50eb452398a16eTest
https://doi.org/10.3390/ijms22052771Test

المؤلفون: Rüdiger Köhling, Simone Baltrusch, Christin Kretzschmar, Anett Sekora, Hugo Murua Escobar, Saleh M. Ibrahim, Markus Tiedge, Katrin Timmer, Georg Fuellen, Christian Junghanss, Catrin Roolf, Gudrun Knübel, Sarah Müller

المصدر: In Vivo. 30:751-760

مصطلحات موضوعية: 0301 basic medicine, Aging, Cancer Research, Mitochondrial DNA, Respiratory chain, Mean corpuscular hemoglobin, Mice, Inbred Strains, 030204 cardiovascular system & hematology, DNA, Mitochondrial, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Hemoglobins, Mice, Inbred AKR, 03 medical and health sciences, chemistry.chemical_compound, Adenosine Triphosphate, 0302 clinical medicine, Erythroid Cells, Species Specificity, medicine, Animals, Cells, Cultured, Cellular Senescence, Pharmacology, chemistry.chemical_classification, Reactive oxygen species, medicine.diagnostic_test, Respiratory chain complex, Mitochondrial Proton-Translocating ATPases, Hematopoietic Stem Cells, Molecular biology, Hematopoiesis, Mice, Inbred C57BL, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, chemistry, Bone marrow, Reactive Oxygen Species, Adenosine triphosphate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8f62a28e1972588ce6aa0f66f029a9Test
https://doi.org/10.21873/invivo.10991Test

المؤلفون: Bernd J. Krause, Anna Richter, Jan Stenzel, Christoph Konkolefski, Saskia Krohn, H. Murua Escobar, Anett Sekora, Brigitte Vollmar, Christian Junghanss, Catrin Roolf, Gudrun Knuebel

المصدر: Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antimetabolites, Antineoplastic, Cell cycle checkpoint, Myeloid, PET/CT, Cell, Azacitidine, Decitabine, Acute lymphoblastic leukemia, lcsh:RC254-282, 03 medical and health sciences, Mice, 0302 clinical medicine, Cell Line, Tumor, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, medicine, Animals, Humans, Doxorubicin, Molecular Biology, B cell, Gene Rearrangement, Chemistry, lcsh:RC633-647.5, Patient-derived xenograft model, Research, Hematology, lcsh:Diseases of the blood and blood-forming organs, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, In vivo imaging, Cancer research, Cytarabine, Bioluminescence, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0042a2d9bb6dfeffddf28b79fe6a9a4Test
https://pubmed.ncbi.nlm.nih.gov/29728108Test

المؤلفون: Stephanie, Schaefer, Juliane, Werner, Sandra, Lange, Christoph, Machka, Gudrun, Knuebel, Anett, Sekora, Catrin, Roolf, Tido, Winkler, Hugo, Murua Escobar, Ingo, Nolte, Christian, Junghanss

المصدر: In vivo (Athens, Greece). 30(4)

مصطلحات موضوعية: Graft Survival, Hematopoietic Stem Cell Transplantation, Graft vs Host Disease, Combined Modality Therapy, Dogs, Histocompatibility, Cyclosporine, Immune Tolerance, Animals, Humans, Transplantation, Homologous, Female, Immunosuppressive Agents, Whole-Body Irradiation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::1c0cdbc5f7ba45f9b898850c5ca69849Test
https://pubmed.ncbi.nlm.nih.gov/27381604Test

المؤلفون: Simone Baltrusch, Gudrun Knübel, Saleh M. Ibrahim, Markus Tiedge, Christin Kretzschmar, Rüdiger Köhling, Anett Sekora, Christian Junghanss, Katrin Timmer, Hugo Murua Escobar, Robert Jaster, Catrin Roolf, Georg Fuellen

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial DNA, Aging, Respiratory chain, Bone Marrow Cells, Biology, medicine.disease_cause, 03 medical and health sciences, Electron Transport Complex III, Gene Knockout Techniques, Mice, Adenosine Triphosphate, Research Paper: Gerotarget (Focus on Aging), medicine, Animals, Progenitor cell, Polymorphism, Genetic, mtDNA, Gerotarget, Age Factors, NADH Dehydrogenase, ROS, medicine.disease, Molecular biology, hematopoiesis, Blood Cell Count, stem cell, Leukemia, Haematopoiesis, Oxidative Stress, 030104 developmental biology, medicine.anatomical_structure, Genes, Mitochondrial, Oncology, Prostaglandin-Endoperoxide Synthases, Immunology, Female, Bone marrow, Stem cell, Reactive Oxygen Species, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73272b6233c94488e4d95b836ee8a48Test
https://pubmed.ncbi.nlm.nih.gov/27626489Test

المؤلفون: Catrin Roolf, Christin Kretzschmar, Georg Fuellen, Christian Junghanss, Robert Jaster, Rüdiger Köhling, Katrin Timmer, Anett Sekora, Gudrun Knübel, Sarah Müller, Hugo Murua Escobar

المصدر: Experimental Hematology. 44:1085-1091.e2

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial ROS, Aging, Cancer Research, medicine.medical_specialty, Neutrophils, Respiratory chain, Bone Marrow Cells, Oxidative phosphorylation, Biology, medicine.disease_cause, Immunophenotyping, Leukocyte Count, Mice, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Internal medicine, Genetics, medicine, Animals, Erythropoiesis, Uncoupling Protein 2, Molecular Biology, Mice, Knockout, chemistry.chemical_classification, B-Lymphocytes, Reactive oxygen species, Cell Biology, Hematology, Mitochondria, Oxidative Stress, Phenotype, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, chemistry, Knockout mouse, Immunology, Bone marrow, Biomarkers, 030217 neurology & neurosurgery, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d530009af2679c4bcbe2d87b122f23Test
https://doi.org/10.1016/j.exphem.2016.08.003Test

المؤلفون: Doreen, Killian, Maria, Reichard, Anne, Knueppel, Sandra, Lange, Anett, Sekora, Gudrun, Knuebel, Hugo, Murua Escobar, Rudolf, Guthoff, Oliver, Stachs, Christian, Junghanss

المصدر: In vivo (Athens, Greece). 27(6)

مصطلحات موضوعية: Dogs, Microscopy, Confocal, Organ Specificity, Epithelium, Corneal, Hematopoietic Stem Cell Transplantation, Mouth Mucosa, Animals, Cell Count, Dendritic Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::c7994fbdfd12bc46e340b0efe2948f35Test
https://pubmed.ncbi.nlm.nih.gov/24292580Test