التفاصيل البيبلوغرافية
| العنوان: |
An antibiotic-resistant class 3 integron in an Enterobacter cloacae isolate from hospital effluent. |
| المؤلفون: |
Barraud, O.1,2,3, Casellas, M.4, Dagot, C.4, Ploy, M.-C.1,2,3, Cantón, R. |
| المصدر: |
Clinical Microbiology & Infection. Jul2013, Vol. 19 Issue 7, pE306-E308. 3p. |
| مصطلحات موضوعية: |
*ANTIBIOTICS, *DRUG resistance, *INTEGRONS, *PLASMIDS, *ENTEROBACTER cloacae, *LACTAMS, *AMINOGLYCOSIDES |
| مستخلص: |
Hospital effluents are involved in dissemination of antibiotic-resistant integrons. We describe here a new class 3 integron, In3-5, detected in an Enterobacter cloacae isolate retrieved from a random French hospital effluent sample collected in 2009. In3-5 carries two gene cassettes: the new bla OXA-256 and an aac(6′)-Ib variant, respectively conferring resistance to β-lactams and aminoglycosides. In3-5 is located on an IncQ-like backbone plasmid. Class 3 integrons could thus be involved in the dissemination of antibiotic resistance in both clinical settings and the environment, and could participate in the exchange of antibiotic-resistance genes between these two ecosystems. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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