نتائج البحث - "Mala Shanmugam"

1

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

المؤلفون: Benjamin G. Barwick, Arusha A. Siddiqa, Anjali Mittal, Samuel K. McBrayer, Changyong Wei, Mala Shanmugam, Deepak Nagrath, Aditi Sharma, Ajay K. Nooka, Richa Bajpai, Abhinav Achreja, Claudia L. Edgar, Vikas Gupta, Sagar Lonial, Manali Rupji, Shannon M. Matulis, Lawrence H. Boise

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Cancer therapy, Molecular biology, Mutant, General Physics and Astronomy, Chromosomal translocation, Myeloma, Pharmacology, Translocation, Genetic, chemistry.chemical_compound, 0302 clinical medicine, lcsh:Science, Multiple myeloma, Thenoyltrifluoroacetone, Sulfonamides, Multidisciplinary, Chemistry, Electron Transport Complex II, Prognosis, 3. Good health, Mitochondria, Enzymes, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Multiple Myeloma, Oxidation-Reduction, musculoskeletal diseases, Cell biology, Science, General Biochemistry, Genetics and Molecular Biology, Article, Electron Transport, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Chromosomes, Human, Pair 14, Electron Transport Complex I, Venetoclax, Chromosomes, Human, Pair 11, Patient Selection, Antagonist, Membrane Proteins, General Chemistry, Metabolism, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, 030104 developmental biology, Cell culture, Drug Resistance, Neoplasm, Mutation, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5d9e6fffd24eed6ab538cbd5ccac4bTest
http://link.springer.com/article/10.1038/s41467-020-15051-zTest

2

Downregulation of PA28α induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma

المؤلفون: Jonathan L. Kaufman, Craig C. Hofmeister, Yanyan Gu, Ajay K. Nooka, Benjamin G. Barwick, Lawrence H. Boise, Mala Shanmugam, Vikas Gupta, Sagar Lonial, Madhav V. Dhodapkar

المصدر: Blood Cancer Journal, Vol 10, Iss 12, Pp 1-10 (2020)
Blood Cancer Journal

مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Down-Regulation, Muscle Proteins, Myeloma, Plasma cell, lcsh:RC254-282, Article, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, medicine, Humans, Multiple myeloma, Eukaryotic cell, biology, Chemistry, Activator (genetics), Hematology, Translational research, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Cell biology, Gene Expression Regulation, Neoplastic, Protein catabolism, 030104 developmental biology, medicine.anatomical_structure, Oncology, Proteasome, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, biology.protein, Antibody, Multiple Myeloma, Proteasome Inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e633d2202ef6627d38e371fc9557fd51Test
https://doi.org/10.1038/s41408-020-00393-0Test

3

Differential effects of PD-L1 versus PD-1 blockade on myeloid inflammation in human cancer

المصدر: JCI Insight

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1d511b19d4ca884124c4fe4e31a4ceTest
https://doi.org/10.1172/jci.insight.129353Test

4

Subpopulation targeting of pyruvate dehydrogenase and GLUT1 decouples metabolic heterogeneity during collective cancer cell invasion

المؤلفون: Wei Zhou, Darius Mahboubi, L. J. Burton, Aditi Sharma, Jessica Konen, R. J. Peterson, Mala Shanmugam, Janna K. Mouw, Adam I. Marcus, Rachel Commander, Yuhong Du, Changyong Wei, Haian Fu, Emily R. Summerbell

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Science, Glucose uptake, Cell, Chemical biology, Collective cell migration, General Physics and Astronomy, Cell Communication, Biology, Oxidative Phosphorylation, Article, General Biochemistry, Genetics and Molecular Biology, Metastasis, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Cell Line, Tumor, Spheroids, Cellular, medicine, Animals, Humans, Neoplasm Invasiveness, Pyruvate Dehydrogenase (Lipoamide), RNA, Small Interfering, lcsh:Science, Cell Proliferation, Glucose Transporter Type 1, Multidisciplinary, Cell growth, Glucose transporter, General Chemistry, Pyruvate dehydrogenase complex, Cancer metabolism, Cell biology, Glucose, 030104 developmental biology, medicine.anatomical_structure, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, lcsh:Q, GLUT1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf48a0697e878a1fbdf81b80301df65eTest
https://doi.org/10.1038/s41467-020-15219-7Test

5

Cancer Metabolism and the Evasion of Apoptotic Cell Death

المؤلفون: Mala Shanmugam, Lawrence H. Boise, Aditi Sharma

المصدر: Cancers, Vol 11, Iss 8, p 1144 (2019)
Cancers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a3144cf2d22fa85532f83205a3df3eTest
https://www.mdpi.com/2072-6694/11/8/1144Test

6

Stromal Support of Metabolic Function through Mitochondrial Transfer in Multiple Myeloma

المؤلفون: Lawrence H. Boise, Mala Shanmugam

المصدر: Cancer Research. 79:2102-2103

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c359811252ed7f030209dfde6d45b894Test
https://doi.org/10.1158/0008-5472.can-19-0500Test

7

Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma

المؤلفون: Sevim Dalva-Aydemir, Mala Shanmugam, Javelin C. Cheng, John D. Carpten, Jonathan K Keats, Cristian Coarfa, Steven T. Rosen, Samuel K. McBrayer, Preethi H. Gunaratne

المصدر: Cancer & Metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e76b7ce54e68a8b7213acd6b54422aTest
https://pubmed.ncbi.nlm.nih.gov/24280290Test

8

Integrative Gene Expression Profiling Reveals G6PD-Mediated Resistance to RNA-Directed Nucleoside Analogues in B-Cell Neoplasms

المؤلفون: Nancy L. Krett, Michael E Yarrington, Varsha Gandhi, Mala Shanmugam, Samuel K. McBrayer, Jun Qian, Steven T. Rosen, Gang Feng

المصدر: PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e41455 (2012)

مصطلحات موضوعية: Adenosine, 2-Chloroadenosine, Microarrays, Chronic lymphocytic leukemia, Cell, Cancer Treatment, lcsh:Medicine, Gene Expression, Lymphoma, Mantle-Cell, Biochemistry, Pentose Phosphate Pathway, 0302 clinical medicine, RNA interference, hemic and lymphatic diseases, Gene expression, Molecular Cell Biology, Basic Cancer Research, RNA, Neoplasm, lcsh:Science, Cancers and neoplasms, Non-Hodgkin lymphoma, Regulation of gene expression, 0303 health sciences, Multidisciplinary, Clinical Trials, Phase I as Topic, Neoplasm Proteins, Nucleic acids, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Hematologic Neoplasms, Carbohydrate Metabolism, Medicine, Lymphomas, Metabolic Pathways, Multiple Myeloma, Research Article, Biology, Glucosephosphate Dehydrogenase, Biosynthesis, Gene Expression Regulation, Enzymologic, Molecular Genetics, 03 medical and health sciences, Cell Line, Tumor, Leukemias, medicine, Humans, Myelomas and Lymphoproliferative Diseases, Nucleic Acid Components, B cell, 030304 developmental biology, Gene Expression Profiling, lcsh:R, Computational Biology, Chemotherapy and Drug Treatment, medicine.disease, Molecular biology, Leukemia, Lymphocytic, Chronic, B-Cell, Gene expression profiling, Metabolism, Cell culture, Drug Resistance, Neoplasm, Hematologic cancers and related disorders, Biocatalysis, RNA, lcsh:Q, Drug Screening Assays, Antitumor, Nucleoside

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752f1251a67801d206ba46615c257de6Test
http://europepmc.org/articles/PMC3407247Test

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