نتائج البحث

1

Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity

المؤلفون: Martin Haupt-Jorgensen, Karsten Buschard, Flemming Pociot, Kristina Pedersen, Knut Dahl-Jørgensen, Ivan C. Gerling, Simranjeet Kaur, Lars Krogvold

المصدر: Diabetologia
Pedersen, K, Haupt-Jorgensen, M, Krogvold, L, Kaur, S, Gerling, I C, Pociot, F, Dahl-Jørgensen, K & Buschard, K 2021, ' Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes : potential contribution to dysregulation of innate antiviral immunity ', Diabetologia, vol. 64, no. 8, pp. 1805-1815 . https://doi.org/10.1007/s00125-021-05469-5Test

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Ribonuclease L, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, Disease, Type 2 diabetes, Biology, Interferon α, RNase L, Type 1 interferon, Antiviral Agents, Polymorphism, Single Nucleotide, Article, Virus, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal Medicine, Genetic predisposition, medicine, Humans, Genetic Predisposition to Disease, RNA, Messenger, Gene, Type 1 diabetes, Oligoribonucleotides, Adenine Nucleotides, RNA-Binding Proteins, medicine.disease, Immunity, Innate, Toll-like receptor 7, Diabetes Mellitus, Type 1, 030104 developmental biology, Gene Expression Regulation, Virus Diseases, Immunology, 2′-5′A pathway, 2′-5′ Oligoadenylate synthetase, Female, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7c11e2de9bab5e6655271157f4e1c3Test
https://doi.org/10.1007/s00125-021-05469-5Test

2

Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes

المؤلفون: Carmella Evans-Molina, Clive Wasserfall, Megan T Legge, Eleni Beli, Craig A. Beam, Ryan Silk, Kieran M. Mcgrail, Linda A. DiMeglio, Mark A. Atkinson, Stephanie Woerner, Maria B. Grant

المصدر: Diabetologia
Beam, C A, Beli, E, Wasserfall, C H, Woerner, S E, Legge, M T, Evans-Molina, C, McGrail, K M, Silk, R, Grant, M B, Atkinson, M A & DiMeglio, L A 2021, ' Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes ', Diabetologia . https://doi.org/10.1007/s00125-021-05468-6Test

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Circadian clock, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Mice, 0302 clinical medicine, Cytotoxic T cell, education.field_of_study, B-Lymphocytes, Immune cells, Flow Cytometry, Circadian Rhythm, Cytokine, Type 1 diabetes, Female, Adult, Adolescent, Period (gene), Population, Biology, Chronobiology Disorders, circadian ryhtms, Article, 03 medical and health sciences, Clinical, Young Adult, Immune system, SDG 3 - Good Health and Well-being, Circadian Clocks, Internal Medicine, medicine, Animals, Humans, Circadian rhythms, Circadian rhythm, Lymphocyte Count, education, Interleukin-6, Dendritic Cells, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Diabetes Mellitus, Type 1, Immune System, Immunology, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5304384a2a7eb86434e13bd1acc63ddbTest
http://europepmc.org/articles/PMC8245361Test

3

Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

المؤلفون: Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pro-Opiomelanocortin, Paraneoplastic Syndromes, Programmed Cell Death 1 Receptor, Autoimmunity, Hypopituitarism, Immune checkpoint inhibitor, medicine.disease_cause, B7-H1 Antigen, Mice, 0302 clinical medicine, Neoplasms, Immunology and Allergy, CTLA-4 Antigen, Corticotrophs, Immune Checkpoint Inhibitors, Aged, 80 and over, biology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Paraneoplastic syndrome, Female, Original Article, Immunotherapy, Antibody, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, Hypophysitis, Immunology, 030209 endocrinology & metabolism, Adrenocorticotropic hormone, 03 medical and health sciences, Antigen, medicine, Animals, Humans, Aged, Retrospective Studies, business.industry, medicine.disease, biology.protein, Ectopic expression, Corticotropic cell, business, Adrenal Insufficiency

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc181a81511e7fe6b828ea748faa32Test
https://hdl.handle.net/20.500.14094/90008773Test

4

Status of humoral and cellular immune markers in human T-cell lymphotropic virus type 1 (HTLV-1) asymptomatic carriers in northeastern Iran, Mashhad

المؤلفون: Farzad Mollahosseini, Mohammad Reza Hedayati-Moghaddam, Mohammad Javad Namazi, Hamid Reza Bidkhori, Narges Valizadeh, Houshang Rafatpanah, Arman Mosavat, Maryam Mahdifar, Seyed Abdolrahim Rezaee

المصدر: Journal of NeuroVirology. 26:863-869

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Cellular immunity, Ki-1 Antigen, Iran, Antibodies, Viral, Lymphocyte Activation, Neopterin, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Immune system, immune system diseases, hemic and lymphatic diseases, Virology, Tropical spastic paraparesis, medicine, Humans, Human T cell lymphotropic virus type 1, Human T-lymphotropic virus 1, Immunity, Cellular, biology, business.industry, Interleukin-2 Receptor alpha Subunit, Antibody titer, virus diseases, Immunoglobulin E, Middle Aged, Viral Load, medicine.disease, HTLV-I Infections, Immunity, Innate, C-Reactive Protein, 030104 developmental biology, Neurology, Case-Control Studies, Asymptomatic Diseases, Immunology, Humoral immunity, biology.protein, Female, Neurology (clinical), Antibody, business, Asymptomatic carrier, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983e40d58566dc048e35e984cb1e8330Test
https://doi.org/10.1007/s13365-020-00910-8Test

5

A Randomized, Phase II Study Evaluating the Efficacy and Safety of Anakinra in the Treatment of Gout Flares

المؤلفون: Robert T. Keenan, S. Ohlman, Kenneth G. Saag, Alexander So, Michael H. Pillinger, Puja P. Khanna, Margareta Wikén, Ann‐Charlotte Åkerblad, Erik Sparve, Lisa Osterling Koskinen, Robert Terkeltaub

المصدر: Arthritis & Rheumatology. 73:1533-1542

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, medicine.medical_specialty, Triamcinolone acetonide, Gout, Visual analogue scale, Immunology, Phases of clinical research, Triamcinolone, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Rheumatology, Internal medicine, medicine, Clinical endpoint, Humans, Immunology and Allergy, Patient Reported Outcome Measures, 030212 general & internal medicine, Adverse effect, Aged, Pain Measurement, Aged, 80 and over, Anakinra, business.industry, Single injection, Middle Aged, Symptom Flare Up, medicine.disease, Arthralgia, Interleukin 1 Receptor Antagonist Protein, Treatment Outcome, Female, business, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c475ce999533edff5cb864ef2dd83dcTest
https://doi.org/10.1002/art.41699Test

6

Soluble form of suppression of tumorigenicity-2 predicts clinical stability of inpatients with community-acquired pneumonia

المؤلفون: Teng Zhang, Peiyan Zheng, Yingjie Zhen, Baoqing Sun, Mingshan Xue, Yifeng Zeng, Xiaohua Douglas Zhang, Runpei Lin, Haisheng Hu, Shixue Sun, Ning Li

المصدر: Exp Biol Med (Maywood)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c238a26cae772385b25e78fe90f3329Test
https://doi.org/10.1177/15353702211027116Test

7

Passive Prophylactic Administration with a Single Dose of Anti–Fel d 1 Monoclonal Antibodies REGN1908–1909 in Cat Allergen–induced Allergic Rhinitis: A Randomized, Double-Blind, Placebo-controlled Clinical Trial

المؤلفون: Ana Kostic, Hanisah Sharif, Constance Ito, Stephen R. Durham, Sava Handijiev, Jiaqian Tang, Iesha Singh, Lubna Kouser, Allen Radin, Neil Stahl, Rebecca Parkin, Mohamed H. Shamji, George D. Yancopoulos, Janice A. Layhadi, Jamie M. Orengo, Claire Q. Wang, Michelle DeVeaux, Mohamed A. Kamal, Angeliki Karamani

المصدر: American Journal of Respiratory and Critical Care Medicine

مصطلحات موضوعية: Male, Allergy, animal diseases, medicine.medical_treatment, Critical Care and Intensive Care Medicine, medicine.disease_cause, 0302 clinical medicine, Allergen, immune system diseases, Fel d 1, Anti-Allergic Agents, 030212 general & internal medicine, Sensitization, Aged, 80 and over, biology, Antibodies, Monoclonal, Middle Aged, respiratory system, medicine.anatomical_structure, Female, Immunotherapy, Adult, Pulmonary and Respiratory Medicine, cat allergy, Asthma and Allergy, Placebo, 03 medical and health sciences, Double-Blind Method, Blocking antibody, Hypersensitivity, otorhinolaryngologic diseases, medicine, Animals, Humans, Immunologic Factors, IgG monoclonal antibodies, Aged, Glycoproteins, Asthma, business.industry, Editorials, Original Articles, Immunoglobulin E, Allergens, Placebo Effect, medicine.disease, Rhinitis, Allergic, respiratory tract diseases, blocking antibodies, 030228 respiratory system, Immunoglobulin G, Immunology, Cats, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c128ae4b94b8773d1daccf673e1f24Test
https://doi.org/10.1164/rccm.202011-4107ocTest

8

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

المساهمون: Institut d'Histoire et de Philosophie des Sciences et des Techniques (IHPST), Université Paris 1 Panthéon-Sorbonne (UP1)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Blood
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩

مصطلحات موضوعية: Adult, Male, MAPK/ERK pathway, CCR2, Myeloid, Cell Survival, MAP Kinase Signaling System, [SDV]Life Sciences [q-bio], Immunology, Chronic myelomonocytic leukemia, Biochemistry, Monocytes, 03 medical and health sciences, Chemokine receptor, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Humans, MCL1, Extracellular Signal-Regulated MAP Kinases, Autocrine signalling, Protein Kinase Inhibitors, Aged, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, Kinase, Chemistry, [SHS.PHIL]Humanities and Social Sciences/Philosophy, Leukemia, Myelomonocytic, Chronic, Blood Proteins, Cell Biology, Hematology, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Cytokines, Myeloid Cell Leukemia Sequence 1 Protein, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a876fc49ce5e247d9cb91a3a300a22Test
https://doi.org/10.1182/blood.2020008729Test

9

Critical COVID‐19 is associated with distinct leukocyte phenotypes and transcriptome patterns

المؤلفون: Kristin Grotle Nore, Sarah Nur, Tuva B. Dahl, Bente Halvorsen, Birgitte Stiksrud, Erik Christensen, Marthe Jøntvedt Jørgensen, Synne Jenum, Kuan Yang, Trine Ranheim, Jan Cato Holter, Anne Ma Dyrhol-Riise, Kristian Tonby, Aleksander Rygh Holten, Camilla Huse, Andreas Lind

المصدر: Journal of Internal Medicine

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Programmed Cell Death 1 Receptor, T cells, Adaptive Immunity, CD8-Positive T-Lymphocytes, 030204 cardiovascular system & hematology, Severity of Illness Index, T-Lymphocytes, Regulatory, Peripheral blood mononuclear cell, Monocytes, Thromboplastin, Transcriptome, transcriptomics, 03 medical and health sciences, 0302 clinical medicine, Immune system, COVID‐19, Internal Medicine, Humans, Medicine, Cytotoxic T cell, IL-2 receptor, Interleukin-7 receptor, B cells, B-Lymphocytes, SARS-CoV-2, business.industry, flow cytometry, Interleukin-7, Interleukin-2 Receptor alpha Subunit, COVID-19, Original Articles, HLA-DR Antigens, Middle Aged, Acquired immune system, Immunity, Innate, Phenotype, 030104 developmental biology, Immunology, Leukocytes, Mononuclear, Original Article, Female, Calprotectin, business, Leukocyte L1 Antigen Complex

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474e9aa561c417d8efc350947e1ad65fTest
https://doi.org/10.1111/joim.13310Test

10

Specific Follicular Helper T Cell Signature in Takayasu Arteritis

المصدر: Arthritis & Rheumatology. 73:1233-1243

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, Receptors, CXCR5, 0301 basic medicine, T Follicular Helper Cells, Receptors, Antigen, T-Cell, alpha-beta, Antigens, CD19, Giant Cell Arteritis, Programmed Cell Death 1 Receptor, Immunology, C-C chemokine receptor type 6, CXCR3, CD19, Immunophenotyping, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Nitriles, Humans, Janus Kinase Inhibitors, Immunology and Allergy, Aorta, Aged, Cell Proliferation, Aged, 80 and over, 030203 arthritis & rheumatology, CD20, B-Lymphocytes, biology, Gene Expression Profiling, T-cell receptor, Middle Aged, Antigens, CD20, Takayasu Arteritis, CCL20, Pyrimidines, Tertiary Lymphoid Structures, 030104 developmental biology, Immunoglobulin G, biology.protein, Pyrazoles, Female, Antibody, Transcriptome, Immunologic Memory

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76692d042d6cf40de5cf9b41f4eefd2eTest
https://doi.org/10.1002/art.41672Test

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