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المؤلفون: Anthony C Keech, Yoon Hi Cho, Ryan J. Farr, Emma S. Scott, David N O'Neal, Anandwardhan A. Hardikar, Paul Z. Benitez-Aguirre, Mugdha V. Joglekar, Andrzej S. Januszewski, Luke M. Carroll, Alicia J. Jenkins, Maria E. Craig, Yik Wen Loh, Wilson K. M. Wong, Kim C. Donaghue
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reportsمصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, Diabetes duration, medicine.medical_treatment, Autoimmunity, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, Medicine, Child, Aged, 80 and over, Multidisciplinary, C-Peptide, Age Factors, Middle Aged, Type 1 diabetes, Female, Adult, medicine.medical_specialty, Adolescent, Science, 030209 endocrinology & metabolism, Article, Young Adult, 03 medical and health sciences, Diabetes mellitus, Internal medicine, microRNA, Humans, Secretion, Circulating MicroRNA, Insulin secretion, Aged, Autoantibodies, Glycated Hemoglobin, business.industry, Insulin, medicine.disease, MicroRNAs, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Genetic markers, Age of onset, business, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd5b712c5082c4c879f559920494d80Test
https://doaj.orgTest/article /b1ec56fdb12a4c0cb5cb32be78d2f006 -
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المؤلفون: Martin Haupt-Jorgensen, Karsten Buschard, Flemming Pociot, Kristina Pedersen, Knut Dahl-Jørgensen, Ivan C. Gerling, Simranjeet Kaur, Lars Krogvold
المصدر: Diabetologia
Pedersen, K, Haupt-Jorgensen, M, Krogvold, L, Kaur, S, Gerling, I C, Pociot, F, Dahl-Jørgensen, K & Buschard, K 2021, ' Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes : potential contribution to dysregulation of innate antiviral immunity ', Diabetologia, vol. 64, no. 8, pp. 1805-1815 . https://doi.org/10.1007/s00125-021-05469-5Testمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Ribonuclease L, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, Disease, Type 2 diabetes, Biology, Interferon α, RNase L, Type 1 interferon, Antiviral Agents, Polymorphism, Single Nucleotide, Article, Virus, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal Medicine, Genetic predisposition, medicine, Humans, Genetic Predisposition to Disease, RNA, Messenger, Gene, Type 1 diabetes, Oligoribonucleotides, Adenine Nucleotides, RNA-Binding Proteins, medicine.disease, Immunity, Innate, Toll-like receptor 7, Diabetes Mellitus, Type 1, 030104 developmental biology, Gene Expression Regulation, Virus Diseases, Immunology, 2′-5′A pathway, 2′-5′ Oligoadenylate synthetase, Female, Genome-Wide Association Study
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7c11e2de9bab5e6655271157f4e1c3Test
https://doi.org/10.1007/s00125-021-05469-5Test -
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المؤلفون: Carmella Evans-Molina, Clive Wasserfall, Megan T Legge, Eleni Beli, Craig A. Beam, Ryan Silk, Kieran M. Mcgrail, Linda A. DiMeglio, Mark A. Atkinson, Stephanie Woerner, Maria B. Grant
المصدر: Diabetologia
Beam, C A, Beli, E, Wasserfall, C H, Woerner, S E, Legge, M T, Evans-Molina, C, McGrail, K M, Silk, R, Grant, M B, Atkinson, M A & DiMeglio, L A 2021, ' Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes ', Diabetologia . https://doi.org/10.1007/s00125-021-05468-6Testمصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Circadian clock, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Mice, 0302 clinical medicine, Cytotoxic T cell, education.field_of_study, B-Lymphocytes, Immune cells, Flow Cytometry, Circadian Rhythm, Cytokine, Type 1 diabetes, Female, Adult, Adolescent, Period (gene), Population, Biology, Chronobiology Disorders, circadian ryhtms, Article, 03 medical and health sciences, Clinical, Young Adult, Immune system, SDG 3 - Good Health and Well-being, Circadian Clocks, Internal Medicine, medicine, Animals, Humans, Circadian rhythms, Circadian rhythm, Lymphocyte Count, education, Interleukin-6, Dendritic Cells, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Diabetes Mellitus, Type 1, Immune System, Immunology, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5304384a2a7eb86434e13bd1acc63ddbTest
http://europepmc.org/articles/PMC8245361Test -
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المؤلفون: Jacqueline V. Schiesser, Thomas Loudovaris, Helen E. Thomas, Edouard G. Stanley, Andrew G. Elefanty
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cell type, medicine.medical_treatment, Science, Cell, Integrin, Gene Expression, Biology, Immunofluorescence, Article, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, medicine, Humans, Insulin, Receptors, Vitronectin, Beta (finance), geography, Multidisciplinary, geography.geographical_feature_category, medicine.diagnostic_test, Cluster of differentiation, Middle Aged, Islet, Gene expression profiling, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Type 1 diabetes, Diabetes Mellitus, Type 1, biology.protein, Medicine, Female, 030217 neurology & neurosurgery, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932b8419e0cfd10e677c6085465d5e16Test
https://doaj.orgTest/article /dcab1ff3fe334cd4b5b2b617cf023918 -
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المؤلفون: Nadir Kadri, Sarah J. Richardson, Lydia Sorokin, Eva Korpos, Sophie Loismann, Clais R. Findeisen, Noel G. Morgan, Alberto Pugliese, Frank Arfuso, George W. Burke, Marika Bogdani
المصدر: Diabetologia
مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Endocrinology, Diabetes and Metabolism, Autoimmunity, medicine.disease_cause, Mice, 0302 clinical medicine, Tertiary lymphoid organs, Mice, Inbred NOD, Child, NOD mice, Aged, 80 and over, Middle Aged, medicine.anatomical_structure, Type 1 diabetes, Fibroblastic reticular cells, Child, Preschool, Lymph node, Female, Beta cell, Adult, medicine.medical_specialty, Basement membrane, Adolescent, T cell, High endothelial venules, 030209 endocrinology & metabolism, Biology, Article, 03 medical and health sciences, Islets of Langerhans, Young Adult, Internal Medicine, medicine, Animals, Humans, Pancreas, B cell, Aged, Autoantibodies, Transplantation, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Tertiary Lymphoid Structures, Microscopy, Fluorescence, Reticular fibres, Insulitis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f333af12269efbba20d5e0fefe7a11dfTest
http://europepmc.org/articles/PMC8187221Test -
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المؤلفون: Amelia K. Linnemann, Charanya Muralidharan, Abass M. Conteh, Pascal de Boer, Jeroen Kuipers, Michelle Marasco, Justin J. Crowder
المصدر: Diabetologia, 64(4), 865-877. SPRINGER
Diabetologiaمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Autophagosome, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Autophagy-Related Proteins, Nod, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Insulin-Secreting Cells, Internal medicine, Diabetes mellitus, Macroautophagy, Internal Medicine, medicine, Autophagy, Animals, Humans, NOD mice, Proinsulin, Type 1 diabetes, business.industry, Autoantibody-positive, medicine.disease, Lysosome, Disease Models, Animal, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Crinophagy, Case-Control Studies, Female, Beta cell, Lysosomes, business, 030217 neurology & neurosurgery, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca8a2e71e6e61e43eb7bea2f3d7a3e4Test
https://doi.org/10.1007/s00125-021-05387-6Test -
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المؤلفون: Sari Niinistö, Carin Andrén Aronsson, Nicole Frank, Roy N. Tamura, Anette-G. Ziegler, Randi K. Johnson, Jill M. Norris, Jorma Toppari, Ulla Uusitalo, Suvi M. Virtanen, Marian Rewers, William Hagopian, Jeffrey P. Krischer, Jimin Yang, Beena Akolkar
المصدر: Diabetologia
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Glutens, Offspring, Pregnancy Trimester, Third, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, The Environmental Determinants of Diabetes in the Young, Autoimmunity, 030209 endocrinology & metabolism, medicine.disease_cause, Diet Surveys, Article, Food group, Eating, Islets of Langerhans, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Risk Factors, Environmental health, Internal Medicine, medicine, Humans, Autoantibodies, Type 1 diabetes, Proportional hazards model, business.industry, Insulin, Postpartum Period, Infant, Newborn, Maternal Nutritional Physiological Phenomena, medicine.disease, Diet, Breast Feeding, Diabetes Mellitus, Type 1, 030104 developmental biology, Female, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec25b379f034a9ba74d821ec80bb705Test
https://doi.org/10.1007/s00125-021-05446-yTest -
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المؤلفون: Shu-Fen Chiang, Tao-Wei Ke, William Tzu-Liang Chen, Kevin Chih-Yang Huang, Pei-Chen Yang, Tsung-Wei Chen, K. S. Clifford Chao
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reportsمصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Colorectal cancer, T-Lymphocytes, medicine.medical_treatment, Perineural invasion, Apoptosis, CD8-Positive T-Lymphocytes, Ligands, Tumour biomarkers, 0302 clinical medicine, Tumor Microenvironment, Cancer, Aged, 80 and over, Univariate analysis, education.field_of_study, Multidisciplinary, Hazard ratio, Gastroenterology, Middle Aged, Prognosis, Colon cancer, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Tumour immunology, Immunohistochemistry, Medicine, Female, Programmed cell death 1 ligand 2, Colorectal Neoplasms, Cancer microenvironment, Adult, medicine.medical_specialty, Science, Article, Disease-Free Survival, 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, medicine, Humans, education, Aged, Proportional Hazards Models, Chemotherapy, business.industry, Carcinoma, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, 030104 developmental biology, business, Biomarkers, CD8
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31308a0fea618ea45ff2e9e298e8da92Test
https://doaj.orgTest/article /e8eb68cf4800457a80ce9ce67aa48863 -
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المؤلفون: Diana Babaevskaya, Andrey Proshin, Igor Pomytkin, Margarita Oplatchikova, Tatyana Strekalova, Johannes P.J.M. de Munter, D. A. Pavlov, Allan V. Kalueff, Klaus-Peter Lesch, Ekaterina Lysikova, Anna Gorlova, Erik Ch. Wolters, Aleksei Umriukhin
المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience
المصدر: Journal of Cellular and Molecular Medicine, 24(17), 10251-10257. Wiley-Blackwell
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med.مصطلحات موضوعية: Male, Pathology, amyotrophic lateral sclerosis, PROTEIN EXPRESSION, EXPERIMENTAL NEUROINFLAMMATION, REAL TIME POLYMERASE CHAIN REACTION, MOUSE, ANIMAL EXPERIMENT, stem cell therapy, FUS[1‐359]‐tg mice, Mice, 0302 clinical medicine, SUCROSE PREFERENCE TEST, CELECOXIB, BRAIN, MUTATION, FUS[1-359]-tg mice, Neurons, RNA BINDING PROTEIN FUS, Behavior, Animal, celecoxib, LOCOMOTION, Neurodegeneration, TRANSGENIC MOUSE, Brain, DEPRESSION, Riluzole, Spinal Cord, 030220 oncology & carcinogenesis, RNA ISOLATION, CALCIUM BINDING PROTEIN, DRUG EFFECT, medicine.medical_specialty, Short Communication, Short Communications, FUS PROTEIN, MOUSE, IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1, BEHAVIOR, ANIMAL, INTERLEUKIN-1BETA, NEUROINFLAMMATION, 03 medical and health sciences, TAIL SUSPENSION TEST, NONHUMAN, Social Behavior, ELEVATED PLUS MAZE TEST, INTERLEUKIN 1BETA, FRONTOTEMPORAL LOBAR DEGENERATION, Glycogen Synthase Kinase 3 beta, animal model, ANIMALS, ANIMAL, medicine.disease, FUS[1-359]-TG MICE, Molecular medicine, 030104 developmental biology, Mutation, HIPPOCAMPUS, emotionality and cognition, CYCLOOXYGENASE 1, HOME-CAGE ACTIVITY TEST, ABNORMAL BEHAVIOR, SPINAL CORD, GELATINASE B, CYCLOOXYGENASE 2, 0301 basic medicine, MATRIX METALLOPROTEINASES, NERVE CELL, Interleukin-1beta, Anti-Inflammatory Agents, Hippocampus, PREFRONTAL CORTEX, ANIMAL MODEL, UNCLASSIFIED DRUG, neuroinflammation, MARBLE BURYING TEST, ANXIETY, COGNITIVE DEFECT, TISSUE INHIBITOR OF METALLOPROTEINASE 1, PLASTICITY, Amyotrophic lateral sclerosis, NEURONS, MOLECULAR MARKER, Frontotemporal lobar degeneration, STEM CELL, riluzole, Muscle atrophy, GENOTYPE, ANTIINFLAMMATORY ACTIVITY, frontotemporal lobar degeneration, BIOLOGICAL MARKER, GLYCOGEN SYNTHASE KINASE 3BETA, Molecular Medicine, AMYOTROPHIC LATERAL SCLEROSIS, RNA-BINDING PROTEIN FUS, medicine.symptom, ANTIINFLAMMATORY AGENT, medicine.drug, STEM CELL THERAPY, GLYCOGEN SYNTHASE KINASE 3 BETA, CAGE TEST, METABOLISM, ADULT, INFLAMMATION, WESTERN BLOTTING, ANIMAL TISSUE, GENE MUTATION, OPEN FIELD TEST, EMOTION, medicine, Animals, RESIDENT-INTRUDER TEST, ARTICLE, NERVE DEGENERATION, Neuroinflammation, Inflammation, MALE, TUMOR NECROSIS FACTOR, INTRACEREBROVENTRICULAR DRUG ADMINISTRATION, business.industry, SOCIAL BEHAVIOR, ANTI-INFLAMMATORY AGENTS, Cell Biology, FRONTOTEMPORAL DEMENTIA, ANIMAL BEHAVIOR, EMOTIONALITY AND COGNITION, CONTROLLED STUDY, MICE, GLYCOGEN SYNTHASE KINASE 3ALPHA, Cyclooxygenase 2, RILUZOLE, COGNITION, RNA-Binding Protein FUS, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06827f1ecd2f754817e6fe6568533e8Test
https://cris.maastrichtuniversity.nl/en/publications/0162d1c6-abc0-4610-83d0-566d46a45289Test -
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المؤلفون: Munisha Smalley, Mohammad Kohandel, Michelle Przedborski, Saravanan Thiyagarajan, Aaron Goldman
المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biologyمصطلحات موضوعية: Adult, Male, 0301 basic medicine, QH301-705.5, Systems biology, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Medicine (miscellaneous), Cancer immunotherapy, Computational biology, Patient response, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Machine learning, Triple combination, medicine, Humans, Biology (General), Immune Checkpoint Inhibitors, Aged, Response rate (survey), Artificial neural network, Systems Biology, Immunotherapy, Middle Aged, Blockade, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Neural Networks, Computer, General Agricultural and Biological Sciences, Transfer of learning
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637586ed76a4096271521c754b48ecb7Test
https://doaj.orgTest/article /44e3f66755784e83bdb6e51e9bad3437