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المصدر: Journal of Cellular and Molecular Medicine, 24(17), 10251-10257. Wiley-Blackwell
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med.

مصطلحات موضوعية: Male, Pathology, amyotrophic lateral sclerosis, PROTEIN EXPRESSION, EXPERIMENTAL NEUROINFLAMMATION, REAL TIME POLYMERASE CHAIN REACTION, MOUSE, ANIMAL EXPERIMENT, stem cell therapy, FUS[1‐359]‐tg mice, Mice, 0302 clinical medicine, SUCROSE PREFERENCE TEST, CELECOXIB, BRAIN, MUTATION, FUS[1-359]-tg mice, Neurons, RNA BINDING PROTEIN FUS, Behavior, Animal, celecoxib, LOCOMOTION, Neurodegeneration, TRANSGENIC MOUSE, Brain, DEPRESSION, Riluzole, Spinal Cord, 030220 oncology & carcinogenesis, RNA ISOLATION, CALCIUM BINDING PROTEIN, DRUG EFFECT, medicine.medical_specialty, Short Communication, Short Communications, FUS PROTEIN, MOUSE, IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1, BEHAVIOR, ANIMAL, INTERLEUKIN-1BETA, NEUROINFLAMMATION, 03 medical and health sciences, TAIL SUSPENSION TEST, NONHUMAN, Social Behavior, ELEVATED PLUS MAZE TEST, INTERLEUKIN 1BETA, FRONTOTEMPORAL LOBAR DEGENERATION, Glycogen Synthase Kinase 3 beta, animal model, ANIMALS, ANIMAL, medicine.disease, FUS[1-359]-TG MICE, Molecular medicine, 030104 developmental biology, Mutation, HIPPOCAMPUS, emotionality and cognition, CYCLOOXYGENASE 1, HOME-CAGE ACTIVITY TEST, ABNORMAL BEHAVIOR, SPINAL CORD, GELATINASE B, CYCLOOXYGENASE 2, 0301 basic medicine, MATRIX METALLOPROTEINASES, NERVE CELL, Interleukin-1beta, Anti-Inflammatory Agents, Hippocampus, PREFRONTAL CORTEX, ANIMAL MODEL, UNCLASSIFIED DRUG, neuroinflammation, MARBLE BURYING TEST, ANXIETY, COGNITIVE DEFECT, TISSUE INHIBITOR OF METALLOPROTEINASE 1, PLASTICITY, Amyotrophic lateral sclerosis, NEURONS, MOLECULAR MARKER, Frontotemporal lobar degeneration, STEM CELL, riluzole, Muscle atrophy, GENOTYPE, ANTIINFLAMMATORY ACTIVITY, frontotemporal lobar degeneration, BIOLOGICAL MARKER, GLYCOGEN SYNTHASE KINASE 3BETA, Molecular Medicine, AMYOTROPHIC LATERAL SCLEROSIS, RNA-BINDING PROTEIN FUS, medicine.symptom, ANTIINFLAMMATORY AGENT, medicine.drug, STEM CELL THERAPY, GLYCOGEN SYNTHASE KINASE 3 BETA, CAGE TEST, METABOLISM, ADULT, INFLAMMATION, WESTERN BLOTTING, ANIMAL TISSUE, GENE MUTATION, OPEN FIELD TEST, EMOTION, medicine, Animals, RESIDENT-INTRUDER TEST, ARTICLE, NERVE DEGENERATION, Neuroinflammation, Inflammation, MALE, TUMOR NECROSIS FACTOR, INTRACEREBROVENTRICULAR DRUG ADMINISTRATION, business.industry, SOCIAL BEHAVIOR, ANTI-INFLAMMATORY AGENTS, Cell Biology, FRONTOTEMPORAL DEMENTIA, ANIMAL BEHAVIOR, EMOTIONALITY AND COGNITION, CONTROLLED STUDY, MICE, GLYCOGEN SYNTHASE KINASE 3ALPHA, Cyclooxygenase 2, RILUZOLE, COGNITION, RNA-Binding Protein FUS, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06827f1ecd2f754817e6fe6568533e8Test
https://cris.maastrichtuniversity.nl/en/publications/0162d1c6-abc0-4610-83d0-566d46a45289Test

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Long noncoding RNA CCAT1 rs67085638 SNP contribution to the progression of gastric cancer in a Polish population

المؤلفون: Anna Lutkowska, Anna Sowińska, P Hevelke, Tomasz Trzeciak, Tomasz Olesiński, Paweł P. Jagodziński, P. Piotrowski, Tomasz Maj, Adam Balcerek

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Genotype, Colorectal cancer, Science, Polymorphism, Single Nucleotide, Virus, Article, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Stomach Neoplasms, Internal medicine, medicine, SNP, Humans, Genetic Predisposition to Disease, Stage (cooking), Cell Proliferation, Cancer, Polycomb Repressive Complex 1, Multidisciplinary, business.industry, Middle Aged, medicine.disease, Long non-coding RNA, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Risk factors, 030220 oncology & carcinogenesis, Lymphatic Metastasis, Disease Progression, Medicine, Female, RNA, Long Noncoding, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b048c5e692f01429a6b6fd80397356faTest
https://doaj.orgTest/article/ffb5ae3deb654efa87b4414543541935

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Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation

المؤلفون: Geethani Bandara, Young-Eun Cho, Do-Kyun Kim, Ho Min Kim, Ana Olivera, Moon-Chang Baek, Dean D. Metcalfe, Baktiar Karim, Danielle R. Donahue, Hirsh D. Komarow

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Bone disease, Cellular differentiation, Osteoporosis, General Physics and Astronomy, Core Binding Factor Alpha 1 Subunit, Myeloproliferative disease, Mice, 0302 clinical medicine, Osteogenesis, Mast Cells, Systemic mastocytosis, Child, Aged, 80 and over, Multidisciplinary, Cell Differentiation, Osteoblast, Middle Aged, Mast cell, RUNX2, Mechanisms of disease, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, miRNAs, Female, Mastocytosis, Adult, Smad5 Protein, Adolescent, Science, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Smad1 Protein, Extracellular Vesicles, Young Adult, 03 medical and health sciences, Calcification, Physiologic, medicine, Animals, Humans, Aged, Myeloproliferative Disorders, Osteoblasts, business.industry, General Chemistry, medicine.disease, Mice, Inbred C57BL, MicroRNAs, 030104 developmental biology, Cancer research, Bone marrow, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9788d1d89c4175b69ee4b424f3cb7644Test
https://doaj.orgTest/article/5187de6573944f56922f41e7869f5c9c

8

Type 1 diabetes in Africa: an immunogenetic study in the Amhara of North-West Ethiopia

المؤلفون: David I. W. Phillips, Alice Holmes, Hannah F. Wilson, Tanwi Vartak, Diana L. Cousminer, Arla Gamper, Kenyaita M. Hodge, Kim Lorenz, Samuel T. Jerram, Stanley Schwartz, Elisabeth R. Trimble, Alistair J K Williams, Shitaye Alemu Balcha, Abayneh Girma Demisse, R. David Leslie, Struan F.A. Grant, Rajashree Mishra, Benjamin F. Voight

المصدر: Diabetologia
Balcha, S A, Demisse, A G, Mishra, R, Vartak, T, Cousminer, D L, Hodge, K M, Voight, B F, Lorenz, K, Schwartz, S, Jerram, S T, Gamper, A, Holmes, A, Wilson, H F, Williams, A J K, Grant, S F A, Leslie, R D, Phillips, D I W & Trimble, E R 2020, ' Type 1 diabetes in Africa : an immunogenetic study in the Amhara of North-West Ethiopia ', Diabetologia . https://doi.org/10.1007/s00125-020-05229-xTest
Balcha, S A, Demisse, A G, Mishra, R, Vartak, T, Cousminer, D L, Hodge, K M, Voight, B F, Lorenz, K, Schwartz, S, Jerram, S T, Gamper, A, Holmes, A, Wilson, H F, Williams, A J K, Grant, S F A, Leslie, R D, Phillips, D I W & Trimble, E R 2020, ' Type 1 diabetes in Africa an immunogenetic study in the Amhara of North-West Ethiopia ', Diabetologia, vol. 63, no. 10, pp. 2158-2168 . https://doi.org/10.1007/s00125-020-05229-xTest

مصطلحات موضوعية: 0301 basic medicine, Male, autoantibodies, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.disease_cause, Autoimmunity, 0302 clinical medicine, Rural, Age of Onset, Child, Principal Component Analysis, C-Peptide, HLA, Type 1 diabetes, Female, Adult, medicine.medical_specialty, Adolescent, Black People, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, Zinc Transporter 8, Article, 03 medical and health sciences, Young Adult, SDG 3 - Good Health and Well-being, Internal medicine, Diabetes mellitus, medicine, Internal Medicine, Humans, Genomes, Genotyping, Socioeconomic status, Autoantibodies, business.industry, Autoantibody, Heritability, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Africa, rural, Ethiopia, business, genomes, Genome-Wide Association Study, HLA-DRB1 Chains

وصف الملف: application/pdf; text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7630a1051fb351796c4213a9e2aeb1dTest
http://europepmc.org/articles/PMC7476916Test

9

Clonal ZEB1-Driven Mesenchymal Transition Promotes Targetable Oncologic Antiangiogenic Therapy Resistance

المصدر: Cancer research, vol 80, iss 7
Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Drug Resistance, Angiogenesis Inhibitors, 0302 clinical medicine, Stem Cell Research - Nonembryonic - Human, Phytogenic, Antineoplastic Combined Chemotherapy Protocols, Tumor Microenvironment, 2.1 Biological and endogenous factors, Medicine, Aetiology, Cancer, Tumor, Neovascularization, Pathologic, Brain Neoplasms, Brain, Middle Aged, Phenotype, Cell Hypoxia, Up-Regulation, Gene Expression Regulation, Neoplastic, Bevacizumab, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Female, Development of treatments and therapeutic interventions, Stem cell, medicine.symptom, Biotechnology, medicine.drug, Adult, Programmed cell death, Epithelial-Mesenchymal Transition, Oncology and Carcinogenesis, Antineoplastic Agents, Article, Lignans, Cell Line, Young Adult, 03 medical and health sciences, Rare Diseases, Downregulation and upregulation, Cell Line, Tumor, Human Umbilical Vein Endothelial Cells, Animals, Humans, Neoplasm Invasiveness, Chitinase-3-Like Protein 1, Oncology & Carcinogenesis, Neovascularization, Aged, Pathologic, Neoplastic, business.industry, Microarray analysis techniques, Biphenyl Compounds, Mesenchymal stem cell, Zinc Finger E-box-Binding Homeobox 1, Hypoxia (medical), Stem Cell Research, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, Brain Disorders, Brain Cancer, 030104 developmental biology, Gene Expression Regulation, Drug Resistance, Neoplasm, Cancer research, Neoplasm, sense organs, Glioblastoma, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31078c3c37cef95ce34f6641ccd4652aTest
https://doi.org/10.1158/0008-5472.can-19-1305Test

10

Metabolic alterations in immune cells associate with progression to type 1 diabetes

المؤلفون: Heikki Hyöty, Santosh Lamichhane, Jorma Ilonen, Partho Sen, Jorma Toppari, Tuomas Lindeman, Matej Orešič, Esko Kemppainen, Riitta Veijola, María Asunción López-Bascón, Tuukka Rönkkö, Mikael Knip, Tuulia Hyötyläinen, Alex M. Dickens

المساهمون: Lääketieteen ja terveysteknologian tiedekunta - Faculty of Medicine and Health Technology, Tampere University, HUS Children and Adolescents, Children's Hospital, Research Programs Unit, University of Helsinki, CAMM - Research Program for Clinical and Molecular Metabolism, Faculty of Medicine

المصدر: Diabetologia

مصطلحات موضوعية: Male, 0301 basic medicine, PREDICTION, Endocrinology, Diabetes and Metabolism, CHILDHOOD, Autoimmunity, ACTIVATION, Transcriptome, 0302 clinical medicine, Longitudinal Studies, RISK, Aged, 80 and over, Sisätaudit - Internal medicine, Middle Aged, 3. Good health, Type 1 diabetes, Disease Progression, Female, Birth cohort, Adult, FEASIBILITY, Genotype, 030209 endocrinology & metabolism, Ceramides, Peripheral blood mononuclear cell, Article, Islets of Langerhans, Young Adult, 03 medical and health sciences, Metabolomics, Immune system, INFLAMMATION, Lipidomics, Internal Medicine, medicine, Humans, Aged, Autoantibodies, Sphingolipids, business.industry, Sphingolipid metabolism, Autoantibody, Lipid metabolism, Lipid Metabolism, medicine.disease, MICROBIOME, Diabetes Mellitus, Type 1, 030104 developmental biology, Genome-scale metabolic modelling, Peripheral blood mononuclear cells, ANTIBODIES, Immunology, Leukocytes, Mononuclear, 3111 Biomedicine, ISLET AUTOANTIBODIES, business

وصف الملف: application/pdf; fulltext; 1017–1031

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8db141e75e5dead62b6ef2f2c63a3dTest
https://doi.org/10.1007/s00125-020-05107-6Test

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