المؤلفون: Jing Deng

المصدر: Acta Pharmaceutica Sinica B, Vol 7, Iss 1, Pp 18-26 (2017)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, BTK, Bruton׳s tyrosine kinase, T-ALL, T-acute lymphocytic leukemia, Apoptosis, Review, PI3K, phosphatidylinositol-3-kinase, Targeted therapy, NIH, National Institutes of Health, ERK, extracellular signal-regulated kinase, GSK-3, MOMP, mitochondrial outer membrane permeabilization, BCL-2 family, CML, chronic myelogenous leukemia, General Pharmacology, Toxicology and Pharmaceutics, CDK, cyclin-dependent kinase, CLL, chronic lymphocytic leukemia, BAX, BCL-2-associated X protein, GSK-3, glycogen synthase kinase-3, Cell biology, NHL, non-Hodgkin lymphoma, BOK, BCL-2 related ovarian killer, BCL-xL, B-cell lymphoma X long, Programmed cell death, CHOP, cyclophosphamide, hydroxydaunorubicin, oncovin-vincristine and prednisone, FDA, U. S. Food and Drug Administration, PUMA, p53 up-regulated modulator of apoptosis, ASH, American Society of Hematology, BID, BH3 interacting domain death agonist, BH3 profiling, Bcl-xL, BIM, BCL-2-interacting mediator of cell death, Biology, BCL-w (BCL2L2), BCL-2-like protein 2, BCR, B-cell receptor, ER, endoplasmic reticulum, 03 medical and health sciences, Mitochondrial priming, Cyclin-dependent kinase, SLL, small lymphocytic lymphoma, NSCLC, non-small cell lung cancer, Combination therapy, PI3K/AKT/mTOR pathway, ITK, interleukin-2-inducible T-cell kinase, BH3, BCL-2 homology 3, Bcl-2 family, lcsh:RM1-950, ATAP, amphipathic tail-anchoring peptide, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, biology.protein, BAD, BCL-2-associated death promoter protein, MCL, myeloid cell leukemia, BAK, BCL-2 homologous antagonist killer, BCL-2, B-cell lymphoma 2, BFL-1 (BCL2A1), BCL-2-related protein A1, BIK, BCL-2-interacting killer, CR, complete response, EGFR, epidermal growth factor receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd33a3c642c227ee36c739b38c6e8328Test

المؤلفون: Mariella Vicinanza, David C. Rubinsztein

المصدر: Developmental Cell. 53:619-620

مصطلحات موضوعية: 0303 health sciences, Mitochondrial outer membrane permeabilization, Endosome, Cell Biology, Mitochondrion, Biology, urologic and male genital diseases, General Biochemistry, Genetics and Molecular Biology, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Apoptosis, Apoptotic cell death, Molecular Biology, 030217 neurology & neurosurgery, 030304 developmental biology, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4f0e46dad352e3d7c1ada53ba7b73ad9Test
https://doi.org/10.1016/j.devcel.2020.05.030Test

المؤلفون: Joerg Stetefeld, Joanna Rzeszowska-Wolny, Mayur V. Jain, Artur Cieślar-Pobuda, Wiem Chaabane, Saeid Ghavami, Marek J. Łos, Mohamed El-Gazzah, Mehrdad Rafat

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 9, Pp 679-693 (2014)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Cytoplasm, Cancer Research, TMRM, Tetramethylrhodamine methyl ester perchlorate0, HGV-Apoptin, Human gyrovirus apoptin, Apoptosis, MOMP, Mitochondrial outer membrane permeabilization, Mitochondrial apoptosis-induced channel, AIF, Nur77, Annan medicinsk grundvetenskap, AIF, Apoptosis inducing factor, Nuclear Receptor Subfamily 4, Group A, Member 1, Gyrovirus, BCL-XL, B-cell lymphoma extra-large, DISC, Death-inducing signal complex, FADD, Other Basic Medicine, Membrane Potential, Mitochondrial, biology, Apoptosis Inducing Factor, Cytochromes c, virus diseases, Receptors, Death Domain, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, mitochondrial pathway, Mitochondria, Cell biology, Protein Transport, Proto-Oncogene Proteins c-bcl-2, Caspases, Apoptosis-inducing factor, Signal Transduction, CAV-Apoptin, Chicken anemia virus apoptin, Programmed cell death, cyt c, cytochrome c, caspase, Bcl-xL, Models, Biological, lcsh:RC254-282, Article, Cell Line, Viral Proteins, death receptors, Humans, 7AAD, 7-amino-actinomycin D, FADD, Fas-associated death domain, Death domain, Intrinsic apoptosis, MEF, Mouse embryonic fibroblast, cytc, digestive system diseases, Apoptin, biology.protein, Apoptosome

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff91e1764b6bc1727600d6c646b3f55Test
https://doi.org/10.1016/j.neo.2014.08.001Test

المؤلفون: Markus Rehm, Jennifer C. Lennon, Jordi Sebastià, Lorna Flanagan, Maria Eugenia Delgado

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813:819-826

مصطلحات موضوعية: Recombinant Fusion Proteins, Mitochondrial outer membrane permeabilization (MOMP), X-Linked Inhibitor of Apoptosis Protein, Apoptosis, Mitochondrion, Inhibitor of apoptosis, Permeability, Mitochondrial Proteins, 03 medical and health sciences, 0302 clinical medicine, Single-cell analysis, Cell Line, Tumor, Humans, Molecular Biology, Caspase, 030304 developmental biology, 0303 health sciences, biology, Activator (genetics), Intracellular Signaling Peptides and Proteins, Cell Biology, Second mitochondria-derived activator of caspases (Smac), Mitochondria, XIAP, Cell biology, Protein Transport, Cytosol, 030220 oncology & carcinogenesis, Mitochondrial Membranes, Time-lapse live cell imaging, biology.protein, x-Linked inhibitor of apoptosis protein (XIAP), Protein Multimerization, biological phenomena, cell phenomena, and immunity, Apoptosis Regulatory Proteins, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e691c7674ef2a5b4280be22a00aa56cTest
https://doi.org/10.1016/j.bbamcr.2011.02.011Test

المؤلفون: Peter K. Sorger, Sabrina L. Spencer

المصدر: Cell. 144(6):926-939

مصطلحات موضوعية: Programmed cell death, Mitochondrial outer membrane permeabilization, Effector Caspases, Biochemistry, Genetics and Molecular Biology(all), Cell, Intrinsic apoptosis, Apoptosis, Disease, Biology, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, Cell biology, medicine.anatomical_structure, Caspases, Mitochondrial Membranes, medicine, Animals, Humans, Single-Cell Analysis, Systems pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ce9be8349bfaa5944b05d447810f39Test

المؤلفون: Clara Pereira, Manuela Côrte-Real, Björn Johansson, Maria João Sousa, Lucília Saraiva, Rui D. Silva

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1783(7):1286-1302

مصطلحات موضوعية: Programmed cell death, Mitochondrial outer membrane permeabilization, Cell, Apoptosis, Yeast apoptosis, Mitochondrion, Biology, Mitochondrial Proteins, 03 medical and health sciences, Bcl-2 family, Yeasts, medicine, Molecular Biology, 030304 developmental biology, 0303 health sciences, 030302 biochemistry & molecular biology, Apoptotic regulators, Cell Biology, Permeability transition pore, Yeast, Cell biology, Mitochondria, medicine.anatomical_structure, Cell metabolism, Biochemistry, Mitochondrial Membranes, Mitochondrial fragmentation, Signal transduction, Apoptosis Regulatory Proteins, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3e150ebf538cb37cad29a33c41ae8aTest

المؤلفون: Eve Wong, Xin Niu, Carsten Culmsee, David W. Andrews, Philipp Mergenthaler, Jing Yi, Jing Sang, Justin Pogmore, Prabhat Arya, Jialing Lin, Hetal Brahmbhatt, Brian Leber, Michael Daude, Jyoti P. Nandy, Weijia Zhu, Zhi Zhang, Fabian G. R. Ehlert, Ravi K. Jimmidi, Maragani Satyanarayana, Wibke E. Diederich

المصدر: Cell Chemical Biology. 24:493-506.e5

مصطلحات موضوعية: Male, 0301 basic medicine, Programmed cell death, Clinical Biochemistry, Excitotoxicity, Glutamic Acid, Apoptosis, Biology, medicine.disease_cause, Biochemistry, Neuroprotection, Permeability, Article, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Cells, Cultured, bcl-2-Associated X Protein, Neurons, Pharmacology, Mitochondrial outer membrane permeabilization, Binding Sites, Bcl-2 family, HCT116 Cells, Small molecule, Recombinant Proteins, Protein Structure, Tertiary, 3. Good health, Cell biology, Neuroprotective Agents, bcl-2 Homologous Antagonist-Killer Protein, 030104 developmental biology, Liposomes, Mitochondrial Membranes, Molecular Medicine, Female, Protein Multimerization, biological phenomena, cell phenomena, and immunity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad10304f690c6cd6717537f79f0425aTest
https://doi.org/10.1016/j.chembiol.2017.03.011Test