التفاصيل البيبلوغرافية
| العنوان: |
Candidiasis invasora en un receptor de trasplante hepático: tratamiento antifúngico de rescate precoz. (Spanish) |
| العنوان البديل: |
Invasive candidiasis in liver transplant recipients: Early rescue antifungal treatment. (English) |
| المؤلفون: |
Pozo-Laderas, Juan Carlos, Pontes-Moreno, Antonio |
| المصدر: |
Revista Iberoamericana de Micologia; 2011, Vol. 28 Issue 1, p124-128, 5p |
| مصطلحات موضوعية: |
CANDIDIASIS treatment, LIVER transplantation, ANTIFUNGAL agents, POSTOPERATIVE care, CANDIDA, MYCOSES, BIOMARKERS |
| الملخص (بالإنجليزية): |
Background: Some liver transplant recipients could be at risk for candidemia or invasive candidiasis during the immediate postoperative period after transplantation. Prophylaxis is the best strategy to reduce the incidence of invasive fungal infection caused by Candida species in high-risk liver transplant recipients (HR-LTR), but in cases of suspected breakthrough invasive fungal infection due to Candida, both a rapid diagnosis process and early antifungal treatment are the most important factors impacting on the prognosis. Clinical case: We report a case of early rescue treatment with anidulafungin in a HR-LTR with complicated postoperative course. We discuss risk factors, prophylaxis, sensitivity of biomarkers, and characteristics of antifungal management. Conclusions: Early rescue antifungal treatment using candins improves the prognosis in HR-LTR suffering from invasive candidiasis. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Antecedentes: Los receptores de trasplante hepático (RTH) pueden ser pacientes de riesgo para desarrollar candidemia o candidiasis invasora durante el período posoperatorio inmediato al trasplante. La profilaxis es la mejor estrategia para disminuir la incidencia de infección fúngica invasora (IFI) producida por Candida spp. en los receptores de riesgo alto. Pero en los casos de sospecha de aparición de IFI de brecha causada por Candida, un proceso de diagnóstico rápido y el tratamiento antifúngico precoz son los factores con un impacto mayor en el pronóstico. Caso clínico: Presentamos un caso clínico de tratamiento de rescate precoz con anidulafungina en un RTH con curso posoperatorio complicado. Se discuten los factores de riesgo, la profilaxis, la sensibilidad de los biomarcadores y las características del tratamiento antifúngico. Conclusiones: El tratamiento antifúngico de rescate precoz con candinas mejora sensiblemente el pronóstico en pacientes RTH de alto riesgo con IFI por Candida. [ABSTRACT FROM AUTHOR] |
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