Dual effects of leptin in perioperative gas exchange of morbidly obese patients
| العنوان: | Dual effects of leptin in perioperative gas exchange of morbidly obese patients |
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| المؤلفون: | Carlo Ori, Giovanna Ieppariello, Egle Perissinotto, Mirto Foletto, Michele Carron, Giulia Gabellini, Gabriele Martelli |
| المصدر: | PLoS ONE PLoS ONE, Vol 13, Iss 7, p e0199610 (2018) |
| بيانات النشر: | Public Library of Science, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Leptin, Male, Physiology, Peptide Hormones, Normal Distribution, lcsh:Medicine, Gastroenterology, Biochemistry, Body Mass Index, 0302 clinical medicine, Blood serum, 030202 anesthesiology, Weight loss, Risk Factors, Medicine and Health Sciences, Odds Ratio, Respiratory function, lcsh:Science, adipokines, Multidisciplinary, ventilation, Physics, Respiration, Classical Mechanics, Obesity, Morbid, Physiological Parameters, Physical Sciences, Arterial blood, Female, medicine.symptom, Research Article, medicine.medical_specialty, Partial Pressure, Adipokine, Surgical and Invasive Medical Procedures, anesthesia, 03 medical and health sciences, Internal medicine, medicine, Pressure, Humans, Obesity, Perioperative Period, business.industry, Pulmonary Gas Exchange, lcsh:R, Body Weight, Biology and Life Sciences, Perioperative, Probability Theory, Probability Distribution, Hormones, Morbid Obesity, 030228 respiratory system, leptin, obesity, respiration, lcsh:Q, Blood Gas Analysis, business, Physiological Processes, Body mass index, Mathematics, Biomarkers |
| الوصف: | Leptin has shown positive effects on respiratory function in experimental settings. The role of leptin on perioperative respiratory function in morbidly obese patients has not been established. We performed a retrospective analysis of morbidly obese patients undergoing laparoscopic sleeve gastrectomy. Fasting serum leptin and interleukin (IL)-6 were measured preoperatively, and arterial blood gases were obtained pre- and postoperatively. Outcome variables were arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2), and differences in PaO2 and PaCO2 between pre- and postoperative values (ΔPaO2, ΔPaCO2; postoperative minus preoperative). Patients with lower ( |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d70e88c6629aec9ca96d0327b61e23fTest http://europepmc.org/articles/PMC6033419Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1d70e88c6629aec9ca96d0327b61e23f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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