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المؤلفون: Lia Gore, Terri Warren, Cinara D. McCarthy, Joseph Aisner, Amita Patnaik, S. Gail Eckhardt, Robert S. Benjamin, Razelle Kurzrock, Stephen Leong, Joseph E. Eid, Gerard Greig, Kai Habben
المصدر: Clinical Cancer Research. 16:2458-2465
مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Adolescent, Maximum Tolerated Dose, Administration, Oral, Antibodies, Monoclonal, Humanized, Gastroenterology, Receptor, IGF Type 1, Young Adult, Pharmacokinetics, Neoplasms, Internal medicine, Humans, Medicine, Tissue Distribution, Survival rate, Aged, Volume of distribution, business.industry, Antibodies, Monoclonal, Middle Aged, medicine.disease, Survival Rate, Treatment Outcome, Endocrinology, Oncology, Tolerability, Response Evaluation Criteria in Solid Tumors, Pharmacodynamics, Monoclonal, Female, business, Progressive disease
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc4a9972d6870f7f3c49fb184b5ca15Test
https://doi.org/10.1158/1078-0432.ccr-09-3220Test -
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المؤلفون: Kunihiko Takeyama, Wojciech Młynarski, Tomasz Szczepański, Gabriel A. Rabinovich, Margaret A. Shipp, Joerg Faber, Przemyslaw Juszczynski, Andrei V. Krivtsov, Katarzyna Mycko, Jeffery L. Kutok, Jing Ouyang, Anna Gaworczyk, Scott A. Armstrong, Scott J. Rodig, Amit U. Sinha, Evan O'Donnell
المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICETمصطلحات موضوعية: Mll, Adult, Glycans, Cancer Research, CIENCIAS MÉDICAS Y DE LA SALUD, Histone methyltransferase activity, Galectin 1, Oncogene Proteins, Fusion, Inmunología, Receptors, Cell Surface, Biology, Article, Translocation, Genetic, Germline, B Cell Leukemia, Histones, Histone H3, Cell Line, Tumor, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, hemic and lymphatic diseases, Galectin-1, medicine, Humans, Immunologic Factors, Epigenetics, neoplasms, Gene Rearrangement, Regulation of gene expression, Chromosomes, Human, Pair 10, Gene Expression Regulation, Leukemic, Chromosomes, Human, Pair 11, Infant, Patología, purl.org/becyt/ford/3.1 [https], Histone-Lysine N-Methyltransferase, medicine.disease, Fusion protein, Molecular biology, Medicina Básica, Oncology, B-cell leukemia, purl.org/becyt/ford/3 [https], Chromosomes, Human, Pair 4, Chromosomes, Human, Pair 9, Chromatin immunoprecipitation, Myeloid-Lymphoid Leukemia Protein
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865f6aa36f1e37429c5e0faaa562b099Test
https://doi.org/10.1158/1078-0432.ccr-09-2765Test -
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المؤلفون: Eva Kimby, Santiago Montes-Moreno, Lidia Sanchez-Verde, Mohit Aggarwal, Giovanna Roncador, Birger Christensson, Björn E. Wahlin, Luis Francisco Gonzalez, Birgitta Sander
المصدر: Clinical Cancer Research. 16:637-650
مصطلحات موضوعية: Adult, Male, Cancer Research, Pathology, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Population, Follicular lymphoma, Biology, Models, Biological, T-Lymphocytes, Regulatory, Cohort Studies, International Prognostic Index, Antigens, CD, Outcome Assessment, Health Care, Follicular phase, medicine, Humans, education, Lymphoma, Follicular, Aged, Aged, 80 and over, education.field_of_study, CD68, Macrophages, FOXP3, T-Lymphocytes, Helper-Inducer, Middle Aged, Prognosis, medicine.disease, Survival Analysis, Lymphoma, Oncology, Tissue Array Analysis, Cancer research, Female, Apoptosis Regulatory Proteins, CD8, T-Lymphocytes, Cytotoxic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd5ad8c556611ff219ec184159691ceTest
https://doi.org/10.1158/1078-0432.ccr-09-2487Test -
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المؤلفون: Mireille Cantarini, Debashis Sarker, Johanna N. H. Timmer-Bonte, D. Ross Camidge, S. Gail Eckhardt, Stan B. Kaye, Paul D. Smith, Clive Morris, Udai Banerji, Karl D. Lewis, Carla M.L. van Herpen, Roshan Agarwal, Ingrid M.E. Desar, Henk M.W. Verheul, Sarah M. A. George, Kathryn H. Brown
المساهمون: Medical oncology, CCA - Innovative therapy
المصدر: Banerji, U, Camidge, D R, Verheul, H M W, Agarwal, R, Sarker, D, Kaye, S B, Desar, I M E, Timmer-Bonte, J N H, Eckhardt, S G, Lewis, K D, Brown, K H, Cantarini, M V, Morris, C, George, S M A, Smith, P D & van Herpen, C M L 2010, ' The First-in-Human Study of the Hydrogen Sulfate (Hyd-Sulfate) Capsule of the MEK1/2 Inhibitor AZD6244 (ARRY-142886): A Phase I Open-Label Multicenter Trial in Patients with Advanced Cancer ', Clinical Cancer Research, vol. 16, no. 5, pp. 1613-1623 . https://doi.org/10.1158/1078-0432.CCR-09-2483Test
Clinical Cancer Research, 16(5), 1613-1623. American Association for Cancer Research Inc.
Clinical Cancer Research, 16, 5, pp. 1613-23
Clinical Cancer Research, 16, 1613-23مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Maximum Tolerated Dose, MAP Kinase Kinase 2, MAP Kinase Kinase 1, Administration, Oral, Antineoplastic Agents, Capsules, Pharmacology, Pharmacokinetics, Translational research [ONCOL 3], Multicenter trial, Neoplasms, medicine, Humans, Adverse effect, Aged, business.industry, Capsule, Common Terminology Criteria for Adverse Events, Middle Aged, Surgery, Oncology, Pharmacodynamics, Toxicity, Selumetinib, Benzimidazoles, Female, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e614b70a5a313e10cc98772d6a34027Test
https://hdl.handle.net/1871/45600Test -
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المؤلفون: Suzanne Kamel-Reid, Xiangdong Liu, D.H. Kim, Jeffrey H. Lipton, Wei Xu, Hans A. Messner, Lakshmi Sriharsha, Katherine A. Siminovitch
المصدر: Clinical Cancer Research. 15:4750-4758
مصطلحات موضوعية: Adult, Male, Cancer Research, ATP Binding Cassette Transporter, Subfamily B, Adolescent, Genotype, medicine.drug_class, Fusion Proteins, bcr-abl, Antineoplastic Agents, Biology, Polymorphism, Single Nucleotide, Piperazines, Tyrosine-kinase inhibitor, Young Adult, Gene Frequency, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cytochrome P-450 CYP3A, Humans, Genetic Predisposition to Disease, ATP Binding Cassette Transporter, Subfamily B, Member 1, Aged, Glycoproteins, ABL, Myeloid leukemia, Imatinib, Middle Aged, Prognosis, medicine.disease, Neoplasm Proteins, Pyrimidines, Treatment Outcome, Imatinib mesylate, Oncology, Drug Resistance, Neoplasm, Pharmacogenetics, Benzamides, Imatinib Mesylate, Cancer research, ATP-Binding Cassette Transporters, Female, Tyrosine kinase, Octamer Transcription Factor-1, Chronic myelogenous leukemia, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5626d3b718cfe5baa8c0d8b702ede937Test
https://doi.org/10.1158/1078-0432.ccr-09-0145Test -
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المؤلفون: Jan H.M. Schellens, Alwin D. R. Huitema, Hilde Rosing, Rob ter Heine, Marianne Keessen, Jos H. Beijnen, Robert S. Jansen, Roos L. Oostendorp
المصدر: Clinical Cancer Research. 15:4228-4233
مصطلحات موضوعية: Adult, Male, Cancer Research, Administration, Oral, Biological Availability, Docetaxel, Pharmacology, urologic and male genital diseases, Cohort Studies, immune system diseases, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Cytochrome P-450 CYP3A, Humans, In patient, ATP Binding Cassette Transporter, Subfamily B, Member 1, neoplasms, Aged, Ritonavir, business.industry, Oral Docetaxel, virus diseases, Middle Aged, Bioavailability, Oncology, Cytochrome P-450 CYP3A Inhibitors, Female, Taxoids, business, therapeutics, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8713c865c6f40f5f678de4eab5a666f3Test
https://doi.org/10.1158/1078-0432.ccr-08-2944Test -
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المؤلفون: Yoshio Tanji, Yasuhiro Tamaki, Tetsuya Taguchi, Seung Jin Kim, Kenzo Shimazu, Shinzaburo Noguchi, Tomonori Tanei, Koji Morimoto
المصدر: Clinical Cancer Research. 15:4234-4241
مصطلحات موضوعية: Adult, Oncology, Cancer Research, medicine.medical_specialty, Paclitaxel, medicine.medical_treatment, Antigens, Differentiation, Myelomonocytic, CA 15-3, Breast Neoplasms, Aldehyde Dehydrogenase 1 Family, Breast cancer, Antigens, CD, Antigens, Neoplasm, Cancer stem cell, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, skin and connective tissue diseases, Aged, Epirubicin, Chemotherapy, Antibiotics, Antineoplastic, Predictive marker, biology, business.industry, CD44, CD24 Antigen, Retinal Dehydrogenase, Aldehyde Dehydrogenase, Middle Aged, medicine.disease, Antineoplastic Agents, Phytogenic, Neoadjuvant Therapy, DNA-Binding Proteins, Isoenzymes, DNA Topoisomerases, Type II, Hyaluronan Receptors, Ki-67 Antigen, Drug Resistance, Neoplasm, Neoplastic Stem Cells, biology.protein, Female, Stem cell, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ade3d412db06cef1cb0fd38748cd7abTest
https://doi.org/10.1158/1078-0432.ccr-08-1479Test -
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المؤلفون: Zhe Zhang, Amrit Mangat, Mary Jo Fackler, Ritu Nayar, Evangeline Taylor, Steve Goodman, Aeisha Rivers, Saraswati Sukumar, Pedram Argani, Seema A. Khan, Wei Wen Teo, Barbara Susnik
المصدر: Clinical Cancer Research. 15:3802-3811
مصطلحات موضوعية: Adult, Cancer Research, Pathology, medicine.medical_specialty, Breast Neoplasms, Biology, Polymerase Chain Reaction, Sensitivity and Specificity, Nipple discharge, Diagnosis, Differential, Breast Diseases, Cytology, Biomarkers, Tumor, medicine, Humans, Genetic Predisposition to Disease, Mammary Glands, Human, neoplasms, Aged, Ductoscopy, medicine.diagnostic_test, Tumor Suppressor Proteins, Carcinoma, Ductal, Breast, Twist-Related Protein 1, Area under the curve, Nuclear Proteins, Reproducibility of Results, Cancer, Endoscopy, Histology, DNA Methylation, Middle Aged, medicine.disease, Oncology, Nipples, DNA methylation, Cytokines, Papilloma, Female, medicine.symptom, Carcinoma in Situ
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c859af59c3e62b5a8f85d53caaaa16Test
https://doi.org/10.1158/1078-0432.ccr-08-1981Test -
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المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research
مصطلحات موضوعية: Male, X-Box Binding Protein 1, Protein Folding, Cancer Research, CHOP, 0302 clinical medicine, hemic and lymphatic diseases, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, Aged, 80 and over, 0303 health sciences, Gene Expression Regulation, Leukemic, Reverse Transcriptase Polymerase Chain Reaction, Myeloid leukemia, Middle Aged, Prognosis, 3. Good health, DNA-Binding Proteins, Leukemia, Oncology, Leukemia, Myeloid, 030220 oncology & carcinogenesis, Acute Disease, Female, Adult, XBP1, Regulatory Factor X Transcription Factors, Biology, Young Adult, 03 medical and health sciences, medicine, Humans, RNA, Messenger, Aged, 030304 developmental biology, Chromosome Aberrations, Endoplasmic reticulum, medicine.disease, Survival Analysis, Alternative Splicing, Karyotyping, Mutation, CCAAT-Enhancer-Binding Proteins, Cancer research, biology.protein, Unfolded protein response, Calreticulin, Transcription Factor CHOP, Molecular Chaperones, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff699fbbfc791f8272df994e4f0db17eTest
https://doi.org/10.1158/1078-0432.ccr-08-2870Test -
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المؤلفون: Rob Robey, Richard H. Wilson, Susan E. Bates, Andrew J. Dwyer, Clara C. Chen, Ann Rutt, Frank M. Balis, Jame Abraham, Tito Fojo, Barry R. Goldspiel, Olaf Van Tellingen, Maureen Edgerly, Susan Bakke
المصدر: Clin Cancer Res
مصطلحات موضوعية: Adult, Cancer Research, Neutropenia, Adolescent, Metabolic Clearance Rate, Nausea, Tariquidar, medicine.medical_treatment, Pharmacology, Vinblastine, Vinorelbine, Article, Young Adult, Pharmacokinetics, Neoplasms, medicine, Humans, Drug Interactions, ATP Binding Cassette Transporter, Subfamily B, Member 1, Aged, P-glycoprotein, Aged, 80 and over, Chemotherapy, Dose-Response Relationship, Drug, biology, business.industry, Antagonist, Middle Aged, medicine.disease, Antineoplastic Agents, Phytogenic, Oncology, Area Under Curve, Quinolines, biology.protein, medicine.symptom, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8098eebe68daa7cc4fcbff66216205Test
https://doi.org/10.1158/1078-0432.ccr-08-0938Test
