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Role of Inflammation in Pathophysiology of Colonic Disease: An Update

التفاصيل البيبلوغرافية
العنوان: Role of Inflammation in Pathophysiology of Colonic Disease: An Update
المؤلفون: Noha Ahmed Nasef, Sunali Mehta
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 13, p 4748 (2020)
بيانات النشر: MDPI AG, 2020.
سنة النشر: 2020
المجموعة: LCC:Biology (General)
LCC:Chemistry
مصطلحات موضوعية: inflammation, diverticular disease, inflammatory bowel disease, colorectal cancer, colitis associated cancer, microbiota and immune response, Biology (General), QH301-705.5, Chemistry, QD1-999
الوصف: Diseases of the colon are a big health burden in both men and women worldwide ranging from acute infection to cancer. Environmental and genetic factors influence disease onset and outcome in multiple colonic pathologies. The importance of inflammation in the onset, progression and outcome of multiple colonic pathologies is gaining more traction as the evidence from recent research is considered. In this review, we provide an update on the literature to understand how genetics, diet, and the gut microbiota influence the crosstalk between immune and non-immune cells resulting in inflammation observed in multiple colonic pathologies. Specifically, we focus on four colonic diseases two of which have a more established association with inflammation (inflammatory bowel disease and colorectal cancer) while the other two have a less understood relationship with inflammation (diverticular disease and irritable bowel syndrome).
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1422-0067
1661-6596
العلاقة: https://www.mdpi.com/1422-0067/21/13/4748Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test
DOI: 10.3390/ijms21134748
الوصول الحر: https://doaj.org/article/14f976a8d95543efa79b97dece17fbe8Test
رقم الانضمام: edsdoj.14f976a8d95543efa79b97dece17fbe8
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14220067
16616596
DOI:10.3390/ijms21134748