دورية أكاديمية
Germline genetic contribution to the immune landscape of cancer
| العنوان: | Germline genetic contribution to the immune landscape of cancer |
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| المؤلفون: | Sayaman R. W., Saad M., Thorsson V., Hu D., Hendrickx W., Roelands J., Porta-Pardo E., Mokrab Y., Farshidfar F., Kirchhoff T., Sweis R. F., Bathe O. F., Heimann C., Campbell M. J., Stretch C., Huntsman S., Graff R. E., Syed N., Radvanyi L., Shelley S., Wolf D., Marincola F. M., Ceccarelli M., Galon J., Ziv E., Bedognetti D. |
| المساهمون: | Sayaman, R. W., Saad, M., Thorsson, V., Hu, D., Hendrickx, W., Roelands, J., Porta-Pardo, E., Mokrab, Y., Farshidfar, F., Kirchhoff, T., Sweis, R. F., Bathe, O. F., Heimann, C., Campbell, M. J., Stretch, C., Huntsman, S., Graff, R. E., Syed, N., Radvanyi, L., Shelley, S., Wolf, D., Marincola, F. M., Ceccarelli, M., Galon, J., Ziv, E., Bedognetti, D. |
| سنة النشر: | 2021 |
| المجموعة: | IRIS Università degli Studi di Napoli Federico II |
| مصطلحات موضوعية: | cancer immune landscape, cancer immunity, Cancer immunotherapy, germline genetic, GWAS, heritability, iATLAS, Immune subtype, rare variant analysi, TCGA |
| الوصف: | Sayaman, Saad et al. investigate the effect of common and rare germline variants on 139 well-defined immune traits in ∼9000 cancer patients enrolled in TCGA, providing evidence for the impact of germline genetics on the composition and functional orientation of the tumor immune microenvironment. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000627407700018; volume:54; issue:2; firstpage:367; lastpage:386.e8; journal:IMMUNITY; http://hdl.handle.net/11588/844576Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85100382979 |
| DOI: | 10.1016/j.immuni.2021.01.011 |
| الإتاحة: | https://doi.org/10.1016/j.immuni.2021.01.011Test http://hdl.handle.net/11588/844576Test |
| رقم الانضمام: | edsbas.3ED02C73 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.immuni.2021.01.011 |
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