دورية أكاديمية
Safety auxiliary feedback element for the artificial pancreas in type 1 diabetes
| العنوان: | Safety auxiliary feedback element for the artificial pancreas in type 1 diabetes |
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| المؤلفون: | Revert, A., Garelli, Fabricio, Picó, J., de Battista, Hernán, Rossetti, P., Vehi, J., Bondia, J. |
| بيانات النشر: | Institute of Electrical and Electronics Engineers |
| المجموعة: | CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| مصطلحات موضوعية: | Artificial Pancreas, Glucose Control, Hypoglycemia, Insulin-On-Board, Reference Conditioning, Safety, Sliding Mode (Sm), https://purl.org/becyt/ford/2.2Test, https://purl.org/becyt/ford/2Test |
| الوصف: | The artificial pancreas aims at the automatic delivery of insulin for glycemic control in patients with type 1 diabetes, i.e., closed-loop glucose control. One of the challenges of the arti- ficial pancreas is to avoid controller overreaction leading to hypoglycemia, especially in the late postprandial period. In this study, an original proposal based on sliding mode reference conditioning ideas is presented as a way to reduce hypoglycemia events induced by a closed-loop glucose controller. The method is inspired in the intuitive advantages of two-step constrained control algorithms. It acts on the glucose reference sent to the main controller shaping it so as to avoid violating given constraints on the insulin-on-board. Some distinctive features of the proposed strategy are that 1) it provides a safety layer which can be adjusted according to medical criteria; 2) it can be added to closed-loop controllers of any nature; 3) it is robust against sensor failures and overestimated prandial insulin doses; and 4) it can handle nonlinear models. The method is evaluated in silico with the ten adult patients available in the FDA-accepted UVA simulator. ; Fil: Revert, A. Universidad Politécnica de Valencia; España ; Fil: Garelli, Fabricio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ingeniería; Argentina ; Fil: Picó, J. Universidad Politécnica de Valencia; España ; Fil: de Battista, Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ingeniería; Argentina ; Fil: Rossetti, P. Universidad Politécnica de Valencia; España ; Fil: Vehi, J. Universidad de Girona; España ; Fil: Bondia, J. Universidad Politécnica de Valencia; España |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0018-9294 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/url/http://ieeexplore.ieee.org/document/6463437Test/; http://hdl.handle.net/11336/23533Test; Revert, A.; Garelli, Fabricio; Picó, J.; de Battista, Hernán; Rossetti, P.; et al.; Safety auxiliary feedback element for the artificial pancreas in type 1 diabetes; Institute of Electrical and Electronics Engineers; Ieee Transactions On Bio-medical Engineering; 60; 8; 3-2013; 2113-2122; CONICET Digital; CONICET |
| الإتاحة: | https://doi.org/10.1109/TBME.2013.2247602Test http://hdl.handle.net/11336/23533Test |
| حقوق: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by-nc-sa/2.5/arTest/ |
| رقم الانضمام: | edsbas.1776CE30 |
| قاعدة البيانات: | BASE |
| تدمد: | 00189294 |
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